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Displaying results 3791 - 3800 of 5449 in total
  1. Drug

    Vadadustat

    go.drugbank.com/drugs/DB12255
    ApprovedInvestigational

    [A244145,A244155] It was first approved in Japan in 2020,[L50371] and in April 2023, it was approved by the EMA for the treatment of symptomatic anemia associated with CKD in adults on chronic maintenance

  2. Drug

    Loprazolam

    go.drugbank.com/drugs/DB13643
    Experimental

    It is a positive modulator of GABA-A receptor that enhances the inhibitory neurotransmission. It is not an FDA-approved drug. … It is indicated for the short-term treatment of insomnia including difficulty in falling asleep and/or frequent nocturnal awakenings.

  3. Drug

    D-Tryptophan

    go.drugbank.com/drugs/DB03225
    Experimental

    The distinguishing structural characteristic of tryptophan is that it contains an indole functional group. It is an essential amino acid as defined by its growth effects on rats. … It is encoded in the standard genetic code as the codon UGG. The D-stereoisomer is occasionally found in naturally produced peptides (for example, the marine venom peptide contryphan).

  4. Drug

    Abivertinib

    go.drugbank.com/drugs/DB15327
    Investigational

    [L17383] It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and B-cell malignancies. … once, it may provide more pronounced clinical benefits as compared to agents targeting single pathways (e.g. interleukin-6 inhibitors).

  5. Drug

    Ivarmacitinib

    go.drugbank.com/drugs/DB16756
    Investigational

    While ivarmactinib has yet to receive marketing authorization, as of February 2022 clinical trials are ongoing or completed evaluating its use in atopic dermatitis,[L40604,L40619,L40629] ankylosing spondylitis

  6. Drug

    Aminorex

    go.drugbank.com/drugs/DB01490
    ExperimentalIllicit

    It may cause pulmonary hypertension.

  7. Drug

    D-Lysine

    go.drugbank.com/drugs/DB03252
    Experimental

    It is often added to animal feed. [PubChem]

  8. Drug

    Motexafin gadolinium

    go.drugbank.com/drugs/DB05428
    Investigational

    It belongs to the family of drugs called metalloporphyrin complexes. Also called gadolinium texaphyrin. … It may make tumor cells more sensitive to radiation therapy, improve tumor images using magnetic resonance imaging (MRI), and kill cancer cells.

  9. Drug

    R1204

    go.drugbank.com/drugs/DB05118
    Experimental

    It is developed for the treatment of depression.

  10. Drug

    XR5944

    go.drugbank.com/drugs/DB06364
    Experimental

    It has both intercalating and antineoplastic activities.