Loprazolam

DB13643ExperimentalSmall molecule

Loprazolam is an imidazobenzodiazepine with anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. It is indicated for the short-term treatment of insomnia including difficulty in falling asleep and/or frequent... Loprazolam is recommended as a short-term therapy only, due to adverse events associated with the drug including dependence and withdrawal symptoms.

Chemical structure of Loprazolam
Mechanism
Curator reviewed
Formula / weight
C23H21ClN6O3 · 464.904 g/mol (avg)
Also known as
Triazulenone
Code names
RU-31158 FREE BASE

Resolves to

Compound
UNII759N8462G8CAS61197-73-7ChEMBLCHEMBL2107448ChEBI135754PubChem3033860
Clinical / RWD
RxNorm38555ATCN05CD11
Structure
InChIKeyUTEFBSAVJNEPTR-RGEXLXHISA-NSMILES[H]\C(N1CCN(C)CC1)=C1\N=C2CN=C(C3=CC=CC=C3Cl)C3=C(C=CC(=C3)N(=O)=O)N2C1=O

What you can answer from here — as of February 21, 2021

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
722Drug interactionsStructured to mechanism, not free text
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1ATC codeIncluding every combination product, plus 12 drug categories
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4+ReferencesStructured and connected to the statements they support
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Which companies are running trials of Loprazolam, in which indications and phases, and which of those programs are still active?

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