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Displaying results 3801 - 3810 of 10000 in total
  1. Drug

    Carotuximab

    go.drugbank.com/drugs/DB06322
    Investigational

    Synonyms: GAMMA1 HEAVY CHAIN (1-448) (MUS MUSCULUS VH (IGHV6-6*01-(IGHD) -IGHJ2*01) (8.10.9) (1-118) -HOMO SAPIENSIGHG1*01, GM17,1 (CH1 (119-216), HINGE (217-231), CH2(232-341), CH3 (342-446), CHS (447-448)) (119, IMMUNOGLOBULIN G1-KAPPA, ANTI-(HUMAN ENDOGLIN (CD105 ANTIGEN)) HUMAN MOUSE CHIMERIC MONOCLONAL ANTIBODY .GAMMA.1 HEAVY CHAIN (1-448) (MOUSE VH (MUS MUSCULUS IGHV6-6*01 (98%) (IGHD)-IGHJ2*01 (87%)) (8.10.9
  2. Drug

    Bepranemab

    go.drugbank.com/drugs/DB17945
    Investigational

    Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau.

    Synonyms: Immunoglobulin g4 (226-proline), anti-(human tau protein) (human-rattus norvegicus monoclonal ucb0107 .gamma.4-chain), disulfide with human-rattus norvegicus monoclonal ucb0107 .kappa.-chain, dimer
  3. Drug

    Trimethyllysine

    go.drugbank.com/drugs/DB03977
    Experimental

    Synonyms: (S)-2-amino-6-(trimethylammonio)hexanoic acid, (S)-5-amino-5-carboxy-N,N,N-trimethyl-1-pentanaminium
  4. Drug

    Perindopril

    go.drugbank.com/drugs/DB00790
    ApprovedInvestigational

    Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS).

    Synonyms: (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acidMixtures: PERAM 4 MG/5 MG TABLET, 30 ADET, RATEN PLUS 4 MG/1.25 MG TABLET
  5. Drug

    Vonlerolizumab

    go.drugbank.com/drugs/DB16352
    Investigational

    Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic

    Synonyms: Immunoglobulin g1-kappa, anti-(human tumor necrosis factor receptor superfamily member 4 (act35 antigen, ox40l receptor, cd134 antigen))humanized mouse monoclonal antibody: .gamma.1 heavy chain (1-447), Immunoglobulin g1-kappa, anti-(homo sapiens tnfrsf4(tumor necrosis factor receptor (tnfr) superfamily member 4, act35, ox40, cd134)), humanized monoclonal antibody
  6. Drug

    OP-145

    go.drugbank.com/drugs/DB05672
    Experimental

    OP-145 is a synthetic antimicrobial peptide developed from human cathelicidin LL-37.

    Synonyms: (4S)-4-(((2S)-2-((2-(((2S,3S)-2-ACETAMIDO-3-METHYL-PENTANOYL)AMINO)ACETYL)AMINO)-6-AMINO-HEXANOYL)AMINO)-5-(((1S)-2-(((1S)-5-AMINO-1-(((1S)-1-(((1S,2S)-1-(((1S)-1-(((1S)-1-(((1S)-1-(((1S,2S)-1-(((1S)-5, -AMINO-1-(((1S)-1-(((1S)-1-BENZYL-2-(((1S)-1-(((1S)-1
  7. Drug

    Ocaratuzumab

    go.drugbank.com/drugs/DB17359
    Investigational

    Ocaratuzumab is a humanized monoclonal antibody directed against CD20. It is being investigated for cancers and autoimmune disorders.

    Synonyms: Immunoglobulin G1, anti-(human B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1, Bp35, leukocyte surface antigen Leu-16, membrane-spanning 4-domains subfamily A member 1))
  8. Drug

    Levamisole

    go.drugbank.com/drugs/DB00848
    ApprovedInvestigationalVet approvedWithdrawn

    [A178123] Interestingly, levamisole has been found as an adulterant in cocaine and can lead to a variety of adverse effects in individuals using this drug.[A178120] … [A178117] It was manufactured by _Janssen_ and first used in 1969 as an agent to treat worm infestations[A178123] Levamisole was approved by the FDA in 1990 as an adjuvant treatment for colon cancer.

    Categories: Heterocyclic Compounds, 1-RingProducts: PARAKS 40 MG TABLET, 6 ADET, PARAKS 40 MG/5 ML ŞURUP, 30 ML
  9. Drug

    Amlitelimab

    go.drugbank.com/drugs/DB18835
    Investigational

    Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years … and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)).

    Synonyms: Immunoglobulin g4 (235-proline,242-glutamic acid), anti-(human ox40 ligand) (human monoclonal ky1005-2d10 .gamma.4-chain), disulfide with human monoclonal ky1005-2d10 .kappa.-chain, dimer
  10. Drug

    Exidavnemab

    go.drugbank.com/drugs/DB19452
    Investigational

    Exidavnemab is under investigation in clinical trial NCT06671938 (Safety, Tolerability, and Pharmacokinetics of Exidavnemab in Patients With Parkinson's Disease).

    Synonyms: Immunoglobulin g4 (226-proline), anti-(human .alpha.-synuclein) (human-mus musculus monoclonal pr-1808164 .gamma.4-chain), disulfide with human-mus musculus monoclonal pr-1808164 .kappa.-chain, dimer