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RAV12
go.drugbank.com/drugs/DB05140InvestigationalRAV12 is investigated for use/treatment in solid tumors. RAV12 is a solid. … RAV12 is a chimeric antibody that recognizes RAAG12, an N-linked carbohydrate antigen found on gastric, colon, pancreatic, prostate, ovarian, breast, and kidney cancer cells.
SN-38
go.drugbank.com/drugs/DB05482InvestigationalSN 38 has been used in trials studying the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung Cancer, Metastatic Colorectal Cancer, and Triple Negative Breast Cancer, among others. … 7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan [DB00762], a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer
Categories: Topoisomerase I InhibitorsMaltotetraose
go.drugbank.com/drugs/DB02237ExperimentalCategories: Compounds used in a research, industrial, or household settingLyme disease vaccine (recombinant OspA)
go.drugbank.com/drugs/DB00045ApprovedWithdrawnLipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as an adjuvant. … Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli.
Ciluprevir
go.drugbank.com/drugs/DB05868InvestigationalThe compound, named BILN 2061, is an orally active inhibitor of the HCV NS3 protease and the first member of this new drug class to be tested in humans.
Alizapride
go.drugbank.com/drugs/DB01425InvestigationalThis kind of pharmacological activity makes it effective for use in the treatment of various kinds of nausea and vomiting, including that which may occur postoperatively. … Alizapride is a dopamine antagonist that is capable of demonstrating both prokinetic and antiemetic effects.
Isosorbide
go.drugbank.com/drugs/DB09401ApprovedInvestigationalIsosorbide was previously available in an oral formulation for the reduction of intraocular pressure. It was approved by the FDA in 1980, but has since been discontinued. … Currently, isosorbide is an organic nitrate currently available in the [isosorbide mononitrate] and [isosorbide dinitrate] forms, and is used for the prevention of angina.
Methyprylon
go.drugbank.com/drugs/DB01107ApprovedIllicitWithdrawnMethyprylon was withdrawn from the U.S. market in June 1965 and the Canadian market in September 1990 due to adverse events. … Methyprylon is a sedative of the piperidinedione derivative family that was previously used for the treatment of insomnia.
Trehalose-6-Phosphate
go.drugbank.com/drugs/DB02430ExperimentalCategories: Compounds used in a research, industrial, or household settingTricaprylin
go.drugbank.com/drugs/DB12176InvestigationalTricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease.
Categories: Compounds used in a research, industrial, or household setting