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Bazedoxifene
go.drugbank.com/drugs/DB06401ApprovedInvestigationalIt is approved in the European Union (marketed in Italy and Spain) and Japan as monotherapy.
Azelastine
go.drugbank.com/drugs/DB00972ApprovedInvestigational[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first granted FDA approval in 1996.
Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen
go.drugbank.com/drugs/DB16710ApprovedInvestigationalIt is contained in the vaccine under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F for intramuscular injection.
Tunicamycin
go.drugbank.com/drugs/DB13172ExperimentalTunicamycin blocks N-linked glycosylation (N-glycans) resulting in cell cycle arrest at the G1 phase in human cells. It is used as an experimental tool to induce unfolded protein response.
KT-333
go.drugbank.com/drugs/DB17165InvestigationalKT-333 is a small molecule targeted protein degrader of STAT3.[L44086]
EI-1071
go.drugbank.com/drugs/DB18486InvestigationalEI-1071 is a selective Colony Stimulating Factor-1 Receptor kinase inhibitor.
Difloxacin
go.drugbank.com/drugs/DB11511ExperimentalVet approvedHowever, it presents a reduced efficacy when compared to other fluoroquinolone antibacterials. … As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration.
Erythropoietin
go.drugbank.com/drugs/DB00016ApprovedInvestigationalIt works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. … It has a molecular weight of approximately 30,400 daltons and is produced by mammalian cells into which the human erythropoietin gene has been introduced.
Products: EPORATIO 20000 I E /1ML, EPORATIO 1000 I E /0.5MLEthanolamine
go.drugbank.com/drugs/DB03994InvestigationalIt is widely distributed in biological tissue and is a component of lecithin. It is used as a surfactant, fluorimetric reagent, and to remove CO2 and H2S from natural gas and other gases.
Thalagen
go.drugbank.com/drugs/DB17714ExperimentalIt is being investigated for the treatment of beta-thalassemia.[L46168] … It consists of autologous CD34-positive hematopoietic progenitor cells transduced with TNS9.3.55, a lentiviral vector encoding the normal human beta-globin gene.