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Corynebacterium diphtheriae CRM197 protein
go.drugbank.com/drugs/DB16712ApprovedInvestigationalMixtures: Prevenar 13 Suspension For InjectionAK119
go.drugbank.com/drugs/DB16423InvestigationalAK119 is a humanized anti-CD73 monoclonal antibody being investigated in the clinical trial NCT04516564 (A Study of AK119 (Anti-CD73 Antibody), a Treatment for COVID-19, in Healthy Subjects).[L28315]
3,4-Methylenedioxy-N-isopropylamphetamine
go.drugbank.com/drugs/DB06112ExperimentalMDI-P is also a potential therapeutic agent for the treatment of the symptoms of cystic fibrosis ("CF"). … MDI-P has been shown to be effective in killing HIV in cell culture. HIV is the virus that causes acquired immune deficiency syndrome (AIDS).
Synonyms: 3,4-Methylenedioxy-N-isopropylamphetamineLobeline
go.drugbank.com/drugs/DB05137InvestigationalIt has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation. [PubChem] … An alkaloid that has actions similar to nicotine on nicotinic cholinergic receptors but is less potent.
Busulfan
go.drugbank.com/drugs/DB01008ApprovedInvestigationalBusulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. … According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: Busulfan Kabi Injection 6mg/ml Concentrate for Solution for Infusion, Busulfan for InjectionIberdomide
go.drugbank.com/drugs/DB12101Investigational[L64055,L64056] It is the first cereblon E3 ligase modulator (CELMoD) approved for multiple myeloma.[L64057] … at least one prior line of therapy including a proteasome inhibitor and an immunomodulatory agent.
Categories: Cereblon E3 ligase modulatorAsimadoline
go.drugbank.com/drugs/DB05104InvestigationalIt has shown encouraging clinical efficacy for the treatment of IBS in a barostat study in IBS patients and has the potential for treating other gastrointestinal diseases. … Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist.
Isoxaflutole
go.drugbank.com/drugs/DB12938ApprovedWithdrawnBalance has been investigated for the treatment of Chronic Renal Failure and Peritoneal Membrane Disorder.
Sucrose
go.drugbank.com/drugs/DB02772ApprovedInvestigationalIt is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener. … A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons.
Categories: Compounds used in a research, industrial, or household setting