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Nitarsone
go.drugbank.com/drugs/DB11437ExperimentalVet approvedIt is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing blackhead disease. It is marketed as Histostat by Zoetis, a publicly traded subsidiary of Pfizer.
ARCoV
go.drugbank.com/drugs/DB15855ExperimentalIt is the first COVID-19 mRNA vaccine to be approved for clinical trials in China, and was co-developed by Abogen Biosciences, Walvax Biotechnolgoy Co., Ltd. and the People’s Liberation Army (PLA) Academy … Preclinical studies in mice and non-human primates has shown that intramuscular administration of ARCoV elicited a Th1-biased cellular response and robust antibodies against SARS-CoV-2[A220048].
Burosumab
go.drugbank.com/drugs/DB14012ApprovedInvestigationalThis is the first drug approved to treat adults and children ages 1 year and older with X-linked hypophosphatemia (XLH), which is a rare, inherited form of rickets.
Ponazuril
go.drugbank.com/drugs/DB11452ExperimentalVet approvedPonazuril, sold by the Bayer Corporation under the trade name Marquis, is a drug currently approved for the treatment of equine protozoal myeloencephalitis in horses, caused by Sarcocystis neurona.
Surotomycin
go.drugbank.com/drugs/DB12076InvestigationalIt is a benzenebutanoic acid derivative patented by Cubist Pharmaceuticals, Inc. as antibacterial agents for the treatment of Gram-positive infections. … Surotomycin is non-inferior to vancomycin and offers a promising alternative for the treatment and prevention of C. diff infection.
AVI-4065
go.drugbank.com/drugs/DB05620InvestigationalIt was developed by Sarepta Therapeutics, Inc. After phase II trials it was cancelled due to lack of potency. [L2917]
INKP-102
go.drugbank.com/drugs/DB05326ExperimentalINKP-102 is the next generation sodium phosphate tablet designed to aid bowl preparation before colonoscopy.
CDX-1135
go.drugbank.com/drugs/DB17607InvestigationalCDX-1135, formerly TP-10, is a soluble, recombinant human Complement Receptor Type 1 (sCR1) developed by Avant Immunotherapeutics (now Celldex).
AAV-AIPL
go.drugbank.com/drugs/DB17857ExperimentalDeveloped by MeiraGTx, it is being investigated for the treatment of inherited retinal dystrophy due to defects in _AIPL1_ gene.
Pyrvinium
go.drugbank.com/drugs/DB06816ApprovedInvestigationalWithdrawnPyrvinium is an anthelmintic effective for pinworms. Several forms of pyrvinium have been prepared with variable counter anions, such as halides, tosylate, triflate and pamoate. Pyrvinum's anti-cancer properties are currently under inves...