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Displaying results 3871 - 3880 of 8517 in total
  1. Drug

    Ataluren

    go.drugbank.com/drugs/DB05016
    ApprovedWithdrawn

    Ataluren is a novel, orally administered drug that targets nonsense mutations. Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk. Mo...

  2. Drug

    Methazolamide

    go.drugbank.com/drugs/DB00703
    Approved

    A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.

  3. Drug

    Alprenolol

    go.drugbank.com/drugs/DB00866
    ApprovedWithdrawn

    One of the adrenergic beta-antagonists used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.

  4. Drug

    PW2101

    go.drugbank.com/drugs/DB06483
    Experimental

    The development of PW2101 has since been discontinued. … The drug was developed by Penwest Pharmaceuticals and in 2005 the FDA issues a Non-Approval letter due to the degree of kinetic variability of PW2101 observed among individuals.

  5. Drug

    Dengue virus serotype 4

    go.drugbank.com/drugs/DB22667
    Approved

    [L53368] Qdenga was approved for use in the European Union in December 2022.[L53373]

  6. Drug

    Dexfenfluramine

    go.drugbank.com/drugs/DB01191
    ApprovedIllicitWithdrawn

    However, following multiple concerns about the cardiovascular side-effects of the drug, such approval was withdrawn.

  7. Drug

    Tasosartan

    go.drugbank.com/drugs/DB01349
    Experimental

    Its long duration of action has been attributed to its active metabolite enoltasosartan. It is used to treat patients with essential hypertension.

  8. Drug

    Benziodarone

    go.drugbank.com/drugs/DB13277
    ApprovedWithdrawn

    It was withdrawn from France markets and British markets due to its effects causing Jaundice in patients [T487, A175636].

  9. Drug

    Methyl-1-testosterone

    go.drugbank.com/drugs/DB01572
    ExperimentalIllicit

    Methyl-1-testosterone is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never marketed for medical use.

  10. Drug

    Microcrystalline cellulose

    go.drugbank.com/drugs/DB14158
    ApprovedInvestigational

    A polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. … As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.