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Omalizumab
go.drugbank.com/drugs/DB00043ApprovedInvestigationalBy binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding to its receptors on immune cells. … [L50482] It is used to treat a range of immune and inflammatory conditions, including allergies, urticaria, and asthma.[A263507]
Categories: Amino Acids, Peptides, and Proteins, Agents to Treat Airway DiseaseProducts: Xolair 150mg Powder and Solvent for Solution for Injection, XOLAIR 150MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTIONDipyridamole
go.drugbank.com/drugs/DB00975ApprovedInvestigationalA phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin.
Mixtures: Aspirin and Dipyridamole, Aspirin and DipyridamoleCategories: Blood and Blood Forming OrgansIsopropyl alcohol
go.drugbank.com/drugs/DB02325ApprovedInvestigationalAn isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
Mixtures: Bus and Classroom Yellow, Care Bus and Classroom YellowCategories: Antiseptics and DisinfectantsVortioxetine
go.drugbank.com/drugs/DB09068ApprovedInvestigationalSome serotonin receptors seem to play a relatively neutral or insignificant role in the regulation of mood, but others, such as 5-HT1A autoreceptors and 5-HT7 receptors, appear to play an oppositional … agonist of 5-HT1A, and an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: KELAC® 10MG, Brintellix 20mg Film-coated TabletsMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalIt is available in the oral tablet form or in solution, and can also be administered through the intravenous route.[T683] Metoclopramide was initially approved by the FDA in 1980.[A184922] … Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system.
Categories: Alimentary Tract and Metabolism, Benzamides and benzamide derivativesSynonyms: 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamideDocetaxel
go.drugbank.com/drugs/DB01248ApprovedInvestigational[A259676] Compared to paclitaxel, docetaxel is two times more potent as an inhibitor of microtubule depolymerization. Docetaxel binds to microtubules but does not interact with dimeric tubulin. … [L46466] Docetaxel was approved by the FDA in 1996 and is available in solution for injection for intravenous or parenteral administration.[A259676]
Categories: Antineoplastic and Immunomodulating AgentsSynonyms: N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol, N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxelDiltiazem
go.drugbank.com/drugs/DB00343ApprovedInvestigationalIt works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle during depolarization. … Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class.
Categories: Calcium-Regulating Hormones and Agents, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseProducts: TİACARD 25MG ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADET, Nu-diltiaz-CD Capsules 120mgTapentadol
go.drugbank.com/drugs/DB06204ApprovedInvestigational[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: PALEXIS® RETARD 25MG, NUCYNTA ER Tablets 250mgLevothyroxine
go.drugbank.com/drugs/DB00451ApprovedInvestigational[F4633] T<sub>4</sub> and T<sub>3</sub> act on nearly every cell of the body, but have a particularly strong effect on the cardiac system. … [F4636,A35722] In response to Thyroid Stimulating Hormone (TSH) release by the pituitary gland, a normally functioning thyroid gland will produce and secrete T<sub>4</sub>, which is then converted through
Mixtures: Levothyroxine and Liothyronine Thyroid, Levothyroxine and Liothyronine ThyroidCategories: Sex Hormones and Insulins, Amino Acids, Peptides, and ProteinsErtugliflozin
go.drugbank.com/drugs/DB11827ApprovedInvestigational[A31581] Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.[L48621] … Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus.
Mixtures: Steglujan (Ertugliflozin 15mg/Sitagliptin 100mg) Film-Coated Tablets, Steglujan (Ertugliflozin 5mg/Sitagliptin 100mg) Film-Coated TabletsCategories: Alimentary Tract and Metabolism, metformin and ertugliflozin