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Displaying results 381 - 390 of 10000 in total
  1. Drug

    4-Carboxy-5-(1-Pentyl)Hexylsulfanyl-1,2,3-Triazole

    go.drugbank.com/drugs/DB04374
    Experimental

    Synonyms: 4-Carboxy-5-(1-Pentyl)Hexylsulfanyl-1,2,3-TriazoleCategories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Lisinopril

    go.drugbank.com/drugs/DB00722
    ApprovedInvestigational

    [A184781,A184808,A184817] ACEIs are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. … [A184853] It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.

    Synonyms: (S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline, [N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-prolineMixtures: LISAM 10 mg/5 mg Tabletten, AMLIPIN 5 / 5 MG FILM TABLET, 30 ADET
  3. Drug

    N-Pyridoxyl-1-Amino-Cyclopropanecarboxylic Acid-5-Monophosphate

    go.drugbank.com/drugs/DB02849
    Experimental

    Synonyms: N-Pyridoxyl-1-Amino-Cyclopropanecarboxylic Acid-5-Monophosphate
  4. Drug

    Fentanyl

    go.drugbank.com/drugs/DB00813
    ApprovedIllicitInvestigationalVet approved

    Fentanyl's high potency has also made it a common adulterant in illicit drugs, especially heroin. … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia.

    Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsSynonyms: N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamide, N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide
  5. Drug

    Sulfamethoxazole

    go.drugbank.com/drugs/DB01015
    ApprovedInvestigational

    [L11830] It is generally given in combination with [trimethoprim], which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps … Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria.

    Synonyms: 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide, 3-(p-Aminophenylsulfonamido)-5-methylisoxazoleMixtures: EUSAPRIM E SUSPENS F ERW, COTRIM E RATIO 480MG/5ML
  6. Drug

    (3S)-N-(5-CHLORO-2-METHYLPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE

    go.drugbank.com/drugs/DB07222
    Experimental

    Synonyms: (3S)-N-(5-CHLORO-2-METHYLPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE
  7. Drug

    Fluorocyclopentenylcytosine

    go.drugbank.com/drugs/DB16168
    Investigational

    Fluorocyclopentenylcytosine is under investigation in clinical trial NCT03189914 (RX-3117 in Combination With Abraxane® in Subjects With Metastatic Pancreatic Cancer).

    Synonyms: 4-amino-1-[(1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-(hydroxymethyl) cyclopent-2-en-1-yl] pyrimidin-2-oneCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Uracil mustard

    go.drugbank.com/drugs/DB00791
    Approved

    It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.

    Synonyms: 5-(di-2-chloroethyl)aminouracil, 5-N,N-bis(2-chloroethyl)aminouracilCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Cinacalcet

    go.drugbank.com/drugs/DB01012
    ApprovedInvestigational

    Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. … It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.

    Synonyms: N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine, (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  10. Drug

    Umeclidinium

    go.drugbank.com/drugs/DB09076
    ApprovedInvestigational

    COPD is a progressive obstructive lung disease characterized by shortness of breath, cough, sputum production, and chronically poor airflow with a forced expiratory volume in 1 second (FEV1) of less than … [A7715] Maintenance of the airway is controlled by the parasympathetic nervous system, particularly by the abundance of the muscarinic subtype 3 (M3) in the airway smooth muscle.

    Mixtures: ANORO ELLIPTA 62.5 MCG + 25 MCG KULLANIMA HAZIR INHALASYON TOZU, 3 X 30 DOZ, ANORO ELLIPTA INHALATION POWDER 62.5 MCG/25 MCGCategories: Cytochrome P-450 Substrates, P-glycoprotein substrates