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Mycophenolate mofetil
go.drugbank.com/drugs/DB00688ApprovedInvestigational[A180826] In addition to the above uses, mycophenolate mofetil has also been studied for the treatment of nephritis and other complications of autoimmune diseases.
Insulin icodec
go.drugbank.com/drugs/DB16693ApprovedInvestigational[L50763] It has also been approved in Japan and Australia.
Undecylenic acid
go.drugbank.com/drugs/DB11117ApprovedUndecylenic acid was first isolated from the products of distillation of castor oil in 1877 via pyrolysis of ricinoleic acid, and has been polymerized for vinyl production [A32281].
RGX-181
go.drugbank.com/drugs/DB17942ExperimentalRGX-181 consists of an adeno-associated virus serotype 9 (AAV9) vector designed to deliver the soluble lysosomal enzyme tripeptidyl peptidase I (TPP1) gene.
LM-609
go.drugbank.com/drugs/DB05787ExperimentalIn addition to cancer, the protein has been implicated in bone destruction in rheumatoid arthritis and the inflammatory process in psoriasis.
VY-HTT01
go.drugbank.com/drugs/DB16999InvestigationalVY-HTT01 is a gene therapy designed to reduce the expression of huntingtin, thereby altering disease progression.
Saprisartan
go.drugbank.com/drugs/DB01347ExperimentalThe mode of (functional) AT1 receptor antagonism has been characterized as insurmountable/noncompetitive for saprisartan.
Sonepcizumab
go.drugbank.com/drugs/DB06305InvestigationalS1P is the extracellular ligand for the G protein-coupled lysophospholipid receptor EDG-1 (endothelial differentiation gene-1).
Mitometh
go.drugbank.com/drugs/DB12117InvestigationalMitometh has been investigated for the treatment of Lung Neoplasms, Untreated Childhood Medulloblastoma, and Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor.
WNY0824
go.drugbank.com/drugs/DB23606Experimental[A274253] It is a dual inhibitor of PLK-1 and BRET-4, which have both been found to be involved in CRPC via suppression of AR/MYC-mediated transcription. [A274258]