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Displaying results 3891 - 3900 of 10000 in total
  1. Drug

    Belnacasan

    go.drugbank.com/drugs/DB05507
    Investigational

    VX-765 is the orally available prodrug of a potent and selective competitive inhibitor of ICE/caspase-1 (VRT-043198). … VX-765 is currently under clinical development for the treatment of inflammatory and autoimmune conditions, as it blocks the hypersensitive response to an inflammatory stimulus.

  2. Drug

    Piclidenoson

    go.drugbank.com/drugs/DB05511
    Investigational

    CF101 is supplied as an oral drug and has an excellent safety profile. … It is also being considered for the treatment of other autoimmune-inflammatory disorders, such as Crohn's disease, psorasis and dry eye syndrome.

    Categories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Mimopezil

    go.drugbank.com/drugs/DB05520
    Experimental

    Mimopezil is a pro-drug that is rapidly absorbed and converted into huperzine A. … Mimopezil is an acetylcholinesterase (AChE) inhibitor that has demonstrated potential use in the treatment of Alzheimer's disease.

    Synonyms: N-(2-Hydroxy-3-methoxy-5-chlorobenzylidene)huperzine A
  4. Drug

    QR-333

    go.drugbank.com/drugs/DB05533
    Investigational

    QR-333 has been investigated as a treatment for diabetic peripheral neuropathy. … QR-333 is a concentrated and standardized nutrient based active compounds dosed in a topical cream designed to reduce oxidative stress and treat symptoms of Diabetic Peripheral Neuropathy, a nerve disorder

  5. Drug

    AMG 108

    go.drugbank.com/drugs/DB05545
    Investigational

    AMG 108 was investigated for use as an antirheumatic agent.

    Categories: Interleukin-1 Receptor Antagonist, Receptors, Interleukin-1, antagonists & inhibitors
  6. Drug

    SB-743921

    go.drugbank.com/drugs/DB05546
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  7. Drug

    Enokizumab

    go.drugbank.com/drugs/DB05555
    Investigational

    A humanized immunoglobulin G1k anti-interleukin-9 mAb.

  8. Drug

    Delcasertib

    go.drugbank.com/drugs/DB05560
    Investigational

    Categories: Protein Kinase C-delta, antagonists & inhibitors
  9. Drug

    Naluzotan

    go.drugbank.com/drugs/DB05562
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT1 Receptor Agonists
  10. Drug

    Ramucirumab

    go.drugbank.com/drugs/DB05578
    ApprovedInvestigational

    Ramucirumab is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. … Ramucirumab is indicated for us in advanced gastric or gastro-esophageal junction adenocarcinoma as a single agent or in combination with paclitaxel after prior fluoropyrimidine- or platinum-containing

    Categories: Vascular Endothelial Growth Factor Receptor 2 AntagonistProducts: CYRAMZA®, CYRAMZA 100MG/10 ML INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇEREN FLAKON, 1 ADET