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Dengue virus serotype 1

[L53368] Qdenga was approved for use in the European Union in December 2022.[L53373]

Zongertinib

[L53873,A274363] On August 8, 2025, the US FDA granted accelerated approval to zongertinib for the treatment of advanced forms of non-small cell lung cancer (NSCLC) with HER2 tyrosine kinase domain

Oleoyl-estrone

This hormone occurs naturally and is found circulating in various animal species and humans. … It has been shown in animal studies to promote the loss of body fat while maintaining body protein storage, maintaining nitrogen balance.

Ularitide

Urodilatin is produced in the kidney and excreted into the urine, and thus exists in low levels naturally in the systemic blood circulation. … Ularitide is currently in Phase 2 development as a potential treatment for patients with acute decompensated heart failure (ADHF).

Indium In-111 oxyquinoline

It is composed of a 3:1 saturated complex of In-111 isotope and oxyquinoline. … Following intravenous administration, the lipid-soluble complex is able to penetrate platelet cell membranes.

OXI-4503

to an orthoquinone chemical species that has direct cytotoxic effects on tumor cells. … OXI-4503 is investigated in clinical trials for treating cancer/tumors. OXI-4503 is a solid. OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis.

Exisulind

Chlormerodrin Hg-197

Chlormerodrin Hg-197 is a radiolabelled form of chlormerodrin, an organomercury compound that was previously used as a diuretic. Its radiolabelled form was used as diagnostics in brain scans.

Chromanol

Chromanol has been used in trials studying the treatment of Prostate Cancer.

Diacerein

It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including severe diarrhea [L780].