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Ulimorelin
go.drugbank.com/drugs/DB12128InvestigationalUlimorelin is a novel small molecule ghrelin agonist being developed by Tranzyme Pharma as a first-in-class treatment for both POI and diabetic gastroparesis, serious medical conditions in which motility … of the GI tract is severely impaired.
Abt-925 anhydrous free base
go.drugbank.com/drugs/DB33803InvestigationalCategories: Receptors, Dopamine D3, antagonists & inhibitorsIndole-3-carbinol
go.drugbank.com/drugs/DB12881InvestigationalIndole 3 Carbinol is under investigation in clinical trial NCT00033345 (Indole-3-Carbinol in Preventing Breast Cancer in Nonsmoking Women Who Are at High Risk For Breast Cancer).
Categories: Compounds used in a research, industrial, or household settingCilomilast
go.drugbank.com/drugs/DB03849InvestigationalFollowing four clinical trials, the drug proved to be effective in treating COPD, however it has never been marketed due to a poor side effect profile. … It is orally active and acts as a selective Phosphodiesterase-4 inhibitor.
Fluorodopa (18F)
go.drugbank.com/drugs/DB13848ApprovedInvestigationalFluorodopa F 18 is a fluorinated analog of [levodopa] used as a diagnostic agent for positron emission tomography (PET) in the evaluation of Parkinsonian syndromes. … [L12849] Fluorodopa F 18 PET is used adjunctly with other diagnostic investigations and serves primarily to visualize dopaminergic nerve terminals in the striatum.[L12849]
Synonyms: L-6-(18F)Fluoro-DOPA, 6-Fluoro-(18F)-L-3,4-DihydroxyphenylalanineAdrafinil
go.drugbank.com/drugs/DB08925ApprovedWithdrawnAdrafinil is a mild central nervous system stimulating drug typically employed to relieve excessive sleepiness and inattention in geriatric patients. … It was marketed in France and elsewhere in Europe under the trade name Olmifon until September 2011 when France's FDA equivalent reassessed the drug and withdrew marketing permission.
Ergometrine
go.drugbank.com/drugs/DB01253ApprovedInvestigationalAn ergot alkaloid with uterine and vascular smooth muscle contractile properties.
Synonyms: D-lysergic acid-L-propanolamide, N-(α-(hydroxymethyl)ethyl)-D-lysergamideVotucalis
go.drugbank.com/drugs/DB05032InvestigationalrEV131 is in development for allergic rhinitis, asthma and several inflammatory eye diseases. It is a topically delivered small protein that acts as an anti-inflammatory agent.
Penicillium glaucum
go.drugbank.com/drugs/DB14171ApprovedPenicillium glaucum allergenic extract is used in allergenic testing.