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Topsalysin
go.drugbank.com/drugs/DB05160InvestigationalTopsalysin is being developed for the treatment of localized prostate cancer and also benign prostatic hyperplasia. Topsalysin is delivered locally to the prostate under ultrasound guidance.
Robenidine
go.drugbank.com/drugs/DB11542ExperimentalVet approvedFarmers alternate the use of robenidine with other antimicrobial agents in order to maintain effectiveness by slowing the development of antimicrobial resistance.
GSK-923295
go.drugbank.com/drugs/DB06097InvestigationalGSK-923295 is the first drug candidate to enter human clinical trials that specifically targets CENP-E and is currently in Phase I human clinical trials being conducted by GSK.
TGAAC94
go.drugbank.com/drugs/DB06175InvestigationalIn 2007, one patient participating in the clinical trial died and the trial was placed on clinical hold by the FDA.
Filgotinib
go.drugbank.com/drugs/DB14845ApprovedInvestigationalRheumatoid arthritis (RA) is a chronic, autoimmune, systemic, and inflammatory disease that causes synovial joint symptoms and can limit range of motion in severe cases. The disease is associated with extra-articular manifestations, prog...
AT-301
go.drugbank.com/drugs/DB16507InvestigationalAT-301 was under investigation in clinical trial NCT01675284 to evaluate the safety, reactogenicity, and humoral immune responses to an inactivated H5N1 influenza vaccine
Virus Specific T-Cell
go.drugbank.com/drugs/DB15735InvestigationalAntigens identified as an immune target are presented by antigen-presenting cells (APCs) to T-cells along with other molecules that stimulate their growth and activation.
Treamid
go.drugbank.com/drugs/DB16365Investigational, Tolerability and Pharmacokinetics of Treamid in Healthy Volunteers) and NCT04527354 (Pilot Study to Assess Efficacy and Safety of Treamid in the Rehabilitation of Patients After COVID-19 Pneumonia) by
Ertiprotafib
go.drugbank.com/drugs/DB06521ExperimentalErtiprotafib belongs to a novel class of insulin sensitizers developed for treatment of type 2 diabetes. In insulin-resistant rodent models, ertiprotafib and a close analog lowered both fasting blood glucose and insulin levels and improv...
Troxacitabine
go.drugbank.com/drugs/DB04961InvestigationalTroxacitabine is a nucleoside analog with antineoplastic activity. There has been growing interest in its development for the treatment of patients with refractory lymphoproliferative conditions.