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SR-123781A
go.drugbank.com/drugs/DB05361InvestigationalIt is under investigation by Sanofi-Aventis and Organon for the treatment of thrombosis and acute coronary syndromes (ACS).
Me-4(18F)DG
go.drugbank.com/drugs/DB19207InvestigationalMe-4(18F)DG is under investigation in clinical trial NCT05558904 (An Investigational Scan (Me-4fdg PET/CT) for the Detection of Sodium-glucose Transport for Early Diagnosis of Lung Cancer).
Zosuquidar
go.drugbank.com/drugs/DB06191InvestigationalIt is now in "Phase 3" of clinical tests in the United States. Its action mechanism consists of the inhibition of P-glycoproteins; other drugs with this mechanism include tariquidar and laniquidar.
AT2220
go.drugbank.com/drugs/DB05200InvestigationalGAA to the lysosome, where it can perform its normal function. … AT2220 has been shown to increase GAA activity in cell lines derived from Pompe patients and in transfected cells expressing misfolded forms of GAA.
BI-K0376
go.drugbank.com/drugs/DB05858ExperimentalBI-K0376 is investigated for use/treatment in acne. BI-K0376 is a solid. It is under investigation by Pfizer and has gone through phase I of the clinical trails.
Testolactone
go.drugbank.com/drugs/DB00894ApprovedWithdrawnAn antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.
Bevirimat
go.drugbank.com/drugs/DB06581InvestigationalIt is not currently FDA-approved, but is undergoing clinical trials conducted by the pharmaceutical company Panacos. … They also show profound effects on scalp and body hair in humans. Bevirimat targets the protein gag-pol polyprotein.
Nitenpyram
go.drugbank.com/drugs/DB11438ExperimentalVet approvedIt is a neonicotinoid, a neurotoxin that blocks neural messages and binds particularly tightly in the central nervous system of insects, causing rapid death. … Nitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets.
Synonyms: (E)-nitenpyram, (1E)-N-((6-chloro-3-pyridinyl)methyl)-N-ethyl-N'-methyl-2-nitro-1,1-ethenediamineCategories: Compounds used in a research, industrial, or household settingIndoprofen
go.drugbank.com/drugs/DB08951ApprovedWithdrawnFollowing reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.
Onvitrelin ucalontide
go.drugbank.com/drugs/DB19183InvestigationalOnvitrelin ucalontide is under investigation in clinical trial NCT01485848 (EP-100 Plus Paclitaxel Versus Paclitaxel Alone in Patients With Ovarian Cancer).
Synonyms: Ep-100 (peptide), Membrane-disrupting peptide ep-100