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Gataparsen
go.drugbank.com/drugs/DB05141InvestigationalLY2181308 is an anti-sense oligonucleotide that potently downregulated survivin expression in human cancer cells derived from lung, colon, breast, prostate, ovary, cervix, skin and brain. … LY2181308 is investigated in clinical trials for treating solid tumors. LY2181308 is a solid. LY2181308 is directed against a molecular target called survivin.
Tienilic acid
go.drugbank.com/drugs/DB04831ApprovedWithdrawnIt was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982)
Naphazoline
go.drugbank.com/drugs/DB06711ApprovedNaphazoline was first developed in 1942 as a nasal formulation for congestion[A176609]. … It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807].
Mixtures: OSMOCROM-N ®, Cooper A.R.Products: Pi Yen Chin, DURAULTRA N SINEN-Ethylmaleimide
go.drugbank.com/drugs/DB02967ExperimentalA sulfhydryl reagent that is widely used in experimental biochemical studies. [PubChem]
Synonyms: N-EthylmaleimideCategories: Compounds used in a research, industrial, or household settingIPH 2101
go.drugbank.com/drugs/DB06049InvestigationalIPH-2101 (NN-1975), a fully human monoclonal antibody developed for patients with acute myeloid leukemia.
Metharbital
go.drugbank.com/drugs/DB00463ApprovedWithdrawnIt was patented in 1905 by Emil Fischer of Merck.
Ferrous asparto glycinate
go.drugbank.com/drugs/DB11169ApprovedFerrous asparto glycinate is an iron-amino acid chelate. It is available as a dietary supplement used in the treatment of iron deficiency and iron deficiency anemia.
Mixtures: Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium Threonate and Succinic AcidMetandienone
go.drugbank.com/drugs/DB13586ApprovedWithdrawnMetandienone is an orally active anabolic androgenic steroid. It was introduced to the market in the 1960s but later discontinued and withdrawn from the market. … Although it is prohibited in and outside competition by the World Anti-Doping Agency, metandienone continues to be marketed and misused as a performance-enhancing drug in sports.
GTI-2501
go.drugbank.com/drugs/DB05406ExperimentalGTI-2501 is a novel antisense drug which has shown a favorable safety profile in preclinical studies, and in a phase I clinical trial. … The drug is in a phase II clinical trial in combination with docetaxel for the treatment of hormone refractory prostate cancer.
Palifermin
go.drugbank.com/drugs/DB00039ApprovedInvestigationalIt is 140 residues long, and is produced using E. coli. Palifermin was granted FDA approval on 15 December 2004.[L17933]