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Rimiducid
go.drugbank.com/drugs/DB04974InvestigationalWhen administered via chemically-inducible dimerization (CID) technologies, rimiducid binds to switch proteins and dimerizes them, triggering downstream signaling cascade. … It was designed to overcome limitations of current cellular immunotherapies used for cancer and other blood disorders by enhancing the control of the immune cell activity and function.
VXA-CoV2-1
go.drugbank.com/drugs/DB16433InvestigationalThis oral vaccine aims to induce immunogenicity through induction of potent serum neutralizing antibodies to the SARS-CoV-2 spike protein, induction of mucosal immune responses, and induction of T-cell … responses to both vaccine antigens of the SARS-CoV-2 nucleocapsid and spike proteins[L30498].
Mito-4509
go.drugbank.com/drugs/DB05846ExperimentalIt is used to treat Parkinson's Disease, Alzheimer's Disease, Retinal Disorders and other neurologic Disorders.
Lortalamine
go.drugbank.com/drugs/DB09187ExperimentalThis drug never made it past clinical trials, likely due to ocular toxicity in animals, but has been used in positron emission tomography studies to label norepinephrine transporters.
(Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide
go.drugbank.com/drugs/DB06941ExperimentalThis compound belongs to the phenylpiperazines. These are compounds containing a phenylpiperazine skeleton, which consists of a piperazine bound to a phenyl group. This drug targets the protein S100B.
Cinaciguat
go.drugbank.com/drugs/DB16126InvestigationalCinaciguat is under investigation in clinical trial NCT01067859 (A Phase Iib Study to Investigate the Efficacy and Tolerability of Lower Doses Cinaciguat (25 ΜG/h, 10 ΜG/h) Given Intravenously to Patients
NBI-6024
go.drugbank.com/drugs/DB05819InvestigationalNBI-6024 is an altered peptide ligand that is designed to cause an immune response which result in preservation of beta-cell function and endogenous insulin production.
2-Methoxyestradiol
go.drugbank.com/drugs/DB02342Investigational2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis).
DDP733
go.drugbank.com/drugs/DB05049InvestigationalSerotonin is a neurotransmitter that is known to be involved in the control of the gastrointestinal (GI) system. … Preclinical studies of DDP733 established the compound’s prokinetic properties (the ability to promote the motility of the GI tract).