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NM-702
go.drugbank.com/drugs/DB05505InvestigationalM-702 is an orally active inhibitor of phosphodiesterase and thromboxane synthetase. … Intermittent claudication is a major symptom of arteriosclerosis obliterans.
Categories: Heterocyclic Compounds, 1-RingBelnacasan
go.drugbank.com/drugs/DB05507InvestigationalVX-765 is the orally available prodrug of a potent and selective competitive inhibitor of ICE/caspase-1 (VRT-043198). … VX-765 is currently under clinical development for the treatment of inflammatory and autoimmune conditions, as it blocks the hypersensitive response to an inflammatory stimulus.
Piclidenoson
go.drugbank.com/drugs/DB05511InvestigationalCF101 is supplied as an oral drug and has an excellent safety profile. … It is also being considered for the treatment of other autoimmune-inflammatory disorders, such as Crohn's disease, psorasis and dry eye syndrome.
Categories: Heterocyclic Compounds, 2-RingMimopezil
go.drugbank.com/drugs/DB05520ExperimentalMimopezil is a pro-drug that is rapidly absorbed and converted into huperzine A. … Mimopezil is an acetylcholinesterase (AChE) inhibitor that has demonstrated potential use in the treatment of Alzheimer's disease.
Synonyms: N-(2-Hydroxy-3-methoxy-5-chlorobenzylidene)huperzine AQR-333
go.drugbank.com/drugs/DB05533InvestigationalQR-333 has been investigated as a treatment for diabetic peripheral neuropathy. … QR-333 is a concentrated and standardized nutrient based active compounds dosed in a topical cream designed to reduce oxidative stress and treat symptoms of Diabetic Peripheral Neuropathy, a nerve disorder
AMG 108
go.drugbank.com/drugs/DB05545InvestigationalAMG 108 was investigated for use as an antirheumatic agent.
Categories: Interleukin-1 Receptor Antagonist, Receptors, Interleukin-1, antagonists & inhibitorsSB-743921
go.drugbank.com/drugs/DB05546InvestigationalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingEnokizumab
go.drugbank.com/drugs/DB05555InvestigationalA humanized immunoglobulin G1k anti-interleukin-9 mAb.
Delcasertib
go.drugbank.com/drugs/DB05560InvestigationalCategories: Protein Kinase C-delta, antagonists & inhibitorsNaluzotan
go.drugbank.com/drugs/DB05562InvestigationalCategories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT1 Receptor Agonists