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Displaying results 3951 - 3960 of 10000 in total
  1. Drug

    Anlotinib

    go.drugbank.com/drugs/DB11885
    Investigational

    Anlotinib has been investigated for the treatment of Non-small Cell Lung Cancer and Metastatic Colorectal Cancer.

    Synonyms: 1-((4-(4-fluoro-2-methyl-1h-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropan-amineCategories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Osugacestat

    go.drugbank.com/drugs/DB12006
    Investigational

    Osugacestat (BMS-906024) has been used in trials studying the treatment of Cancer, Lymphoblastic Leukemia, Acute T-cell, and Precursor T-Cell Lymphoblastic Lymphoma.

    Synonyms: (2R,3S)-N1-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-2,3-bis(3,3,3-trifluoropropyl)succinamide, Butanediamide, N1-((3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-2,3-bis(3,3,3-trifluorophenyl)-, (2R,3S)-Categories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Dimepheptanol

    go.drugbank.com/drugs/DB19094
    Investigational

    Dimepheptanol is under investigation in clinical trial NCT00218127 (Treatment of Opioid/heroin Dependence: Comparison of Three Medication Dosing Regimens).

    Synonyms: .-(2-(dimethylamino)propyl(-.alpha.-ethyl-.beta.-phenyl-, 6-dimethylamino-4,4-diphenyl-3-heptanol
  4. Drug

    Tirabrutinib

    go.drugbank.com/drugs/DB15227
    Investigational

    Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS-4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)).

    Synonyms: 6-amino-9-[(3R)-1-but-2-ynoylpyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-oneCategories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Idursulfase beta

    go.drugbank.com/drugs/DB16190
    Investigational

    Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).

    Synonyms: Iduronate 2-sulfatase (a-l-iduronate sulfate sulfatase), human proenzyme produced in cho cells (glycoform beta)
  6. Drug

    Icalcaprant

    go.drugbank.com/drugs/DB21651
    Investigational

    Icalcaprant is a small molecule drug. The usage of the INN stem '-caprant' in the name indicates that Icalcaprant is a kappa-opioid receptor (KOR) antagonist. … Icalcaprant has a monoisotopic molecular weight of 406.2 Da.

    Synonyms: 4-(4-{[(2S)-2-(3-methoxy-1-methyl-1H-pyrazol-4-yl)pyrrolidin-1-yl]methyl}phenoxy)benzamide
  7. Drug

    Regramostim

    go.drugbank.com/drugs/DB05386
    Investigational

    Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. … Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and macrophages.

    Synonyms: Colony-stimulating factor 2 (human clone pCSF-1 protein moiety reduced), glycoform GMC 89-107, GM-CSF (CHO cell)
  8. Drug

    BG-P-TAT

    go.drugbank.com/drugs/DB18105
    Experimental

    Synonyms: 2-(4-(4-((1-(107-(4-(guanidinomethyl)phenoxy)-(polyethyleneglycol36))-1H-1,2,3-triazol-4-yl)methoxy)-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid
  9. Drug

    EP-0042

    go.drugbank.com/drugs/DB18120
    Investigational

    Synonyms: 3H-IMIDAZO(4,5-B)PYRIDINE, 6-CHLORO-7-(4-((4-CHLOROPHENYL)METHYL)-1-PIPERAZINYL)-2-(1,3-DIMETHYL-1H-PYRAZOL-4-YL)-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    ENMD-981693

    go.drugbank.com/drugs/DB16891
    Investigational

    Synonyms: (E)-N-(5-Methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-styrylpyrimidin-4-amineCategories: Heterocyclic Compounds, 1-Ring