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Gallium Ga-68 gozetotide
go.drugbank.com/drugs/DB16019ApprovedInvestigational[A225396] Ga-68 PSMA-11 is an imaging agent that binds PSMA during positron emission tomography: it emits positrons to indicate the presence of PSMA-positive prostate cancer lesions in patients with suspected … [L43542] In December of the same year, the drug was fully authorized by the EMA.[L44682] In Octer 2022, Ga-68 PSMA-11 was approved by Health Canada for diagnostic use in men with prostate cancer.
Categories: Indicators and Reagents, Compounds used in a research, industrial, or household settingEpoprostenol
go.drugbank.com/drugs/DB01240ApprovedInvestigationalA prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue.
Synonyms: Prostaglandin I2Categories: Blood and Blood Forming Organs, Prostaglandins IDarolutamide
go.drugbank.com/drugs/DB12941ApprovedInvestigational[A189054,A189063] Darolutamide was developed by Bayer HealthCare Pharmaceuticals Inc. and approved by the FDA on July 30th, 2019.[L10887] … The goal of treatment with darolutamide is to delay the progression of prostate cancer to metastatic disease, increasing quality of life and life expectancy for those with advanced prostate cancer.
Categories: Antineoplastic and Immunomodulating Agents, Hormone Antagonists and Related AgentsProducts: NUBEQA FILM-COATED TABLET 300MGPizotifen
go.drugbank.com/drugs/DB06153ApprovedSandomigran is available in a number of countries but is not approved by the FDA nor EMA. … Pizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic management of migraines.
Bordetella pertussis pertactin antigen
go.drugbank.com/drugs/DB10789ApprovedInvestigationalBordetella pertussis pertactin antigen is a vaccine for the prophylaxis of whooping cough that contains pertactin, a membrane-associated antigen of Bordetella pertussis [A31248].
Mixtures: -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE, Covaxis Injektionssuspension in einer FertigspritzeCategories: Amino Acids, Peptides, and ProteinsVoclosporin
go.drugbank.com/drugs/DB11693ApprovedInvestigational[L31218] This [cyclosporine] A analog was approved by the FDA on January 22, 2021 following promising results in clinical trials. … [L31208] Voclosporin has demonstrated a more stable pharmacokinetic and pharmacodynamic relationship than cyclosporine, a higher potency than cyclosporine, and an improved metabolic profile when compared
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsImetelstat
go.drugbank.com/drugs/DB14909ApprovedInvestigationalImetelstat is a first-in-class 18-amino acid oligonucleotide that directly and competitively inhibits human telomerase. … [erythropoietin]), but primary resistance to these agents is frequent - the median response duration is 18 to 24 months, with most responders (70%) relapsing due to loss of sensitivity of erythroid progenitors
Categories: Antineoplastic and Immunomodulating Agents, Nucleic Acids, Nucleotides, and NucleosidesCarprofen
go.drugbank.com/drugs/DB00821ApprovedVet approvedWithdrawnCarprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. … It was generally well tolerated, with the majority of adverse effects being mild, such as gastro-intestinal pain and nausea, similar to those recorded with aspirin and other non-steroidal anti-inflammatory
Tazemetostat
go.drugbank.com/drugs/DB12887ApprovedInvestigational[L11476] Tazemetostat was first named in literature as EPZ-6438.[A190363] Tazemetaostat was granted FDA approval on 23 January 2020.[L11476] … Tazemetostat is a methyltransferase inhibitor used to treat metastatic or locally advanced epithelioid sarcoma not eligible for complete resection.
Categories: Antineoplastic and Immunomodulating Agents, MATE 2-K InhibitorsBone Metastases
go.drugbank.com/conditions/DBCOND0028830Synonyms: Secondary malignant neoplasm of bone and bone marrow