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Hypromellose
go.drugbank.com/drugs/DB11075ApprovedInvestigationalIt is a commonly used as a delivery component in oral pharmaceutical products that provides the release of a drug in a controlled fashion, effectively increasing the duration of release of a drug to prolong … Hypromellose is also found in eye drops as a lubricant [L1803].
Synonyms: Cellulose, 2-hydroxypropyl methyl etherSalts: Hypromellose 2910 (3 mPa.S)Nitisinone
go.drugbank.com/drugs/DB00348ApprovedNitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1 and Alkaptonuria.
Categories: 4-Hydroxyphenyl-Pyruvate Dioxygenase Inhibitor, 4-Hydroxyphenylpyruvate Dioxygenase, antagonists & inhibitorsSynonyms: 2-(alpha,alpha,alpha-Trifluoro-2-nitro-p-tuluoyl)-1,3-cyclohexanedioneFrovatriptan
go.drugbank.com/drugs/DB00998ApprovedFrovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: NEWART 2.5 MG TABLET, 6 ADET, MIGREX 2.5 MG FILM TABLET, 6 ADETErythromycin
go.drugbank.com/drugs/DB00199ApprovedInvestigationalVet approvedIt was originally discovered in 1952.[L5245] Erythromycin is widely used for treating a variety of infections, including those caused by gram-positive and gram-negative bacteria. … Erythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists
Mixtures: ISOTREXIN JEL, 30 G, BENZAMYCIN TOPIKAL JEL, 46.6 GCategories: P-glycoprotein inhibitors, P-glycoprotein substratesHydroxyethyl Starch
go.drugbank.com/drugs/DB09106ApprovedInvestigationalHES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose. … Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume.
Mixtures: VOLUVEN % 6 500 ML SOLUSYON, ISOHES %6 (SETLI) 500 ML SOLUSYONCategories: Compounds used in a research, industrial, or household settingRacepinephrine
go.drugbank.com/drugs/DB11124ApprovedRacepinephrine is a racemic mixture consisting of d-[DB00668] and l-[DB00668] enantiomers. Epinephrine is a non-selective α- and β-adrenergic receptor agonist. … It is a bronchodilator used in the temporary relief of mild symptoms of intermittent asthma including wheezing, tightness of chest and shortness of breath.
Mixtures: Sil Trax Plus No 8, Sil Trax Plus No 9Categories: Adrenergic alpha-1 Receptor Agonists, Adrenergic alpha-2 Receptor AgonistsDextran
go.drugbank.com/drugs/DB09255ApprovedInvestigationalVet approvedDextran is a polysaccharide that differs from others in that its glucose units are joined together 1:6 glucoside links. … The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and 1:4 glucoside links. The chains can be composed of about 200,000 glucose units.
Salts: Dextran 40, Dextran sulfate sodium (MW 5000)Mixtures: Macrodex 6% In Dextrose, Dextran 6% In 5% Dextrose InjectionPacmilimab
go.drugbank.com/drugs/DB18873InvestigationalPacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer).
Synonyms: IMMUNOGLOBULIN G4, ANTI-(HUMAN PROGRAMMED CELL DEATH-LIGAND 1) (HUMAN MONOCLONAL CX-072 .GAMMA.4-CHAIN), DISULFIDE WITH PRODOMAIN PROTEIN (SYNTHETIC MASKING MOIETY AND CLEAVABLE MOIETY PROTEASE SUBSTRATE-CONTAINING, ) FUSION PROTEIN WITH HUMAN MONOCLONAL CUdenafil
go.drugbank.com/drugs/DB06267ApprovedUdenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena. … It is not yet approved for use in the U.S., E.U., or Canada.
Categories: Drugs Used in Erectile Dysfunction, Cytochrome P-450 SubstratesProducts: ZYDENA 100 MG FILM TABLET, 4 ADET, ZYDENA 100 MG FILM TABLET, 2 ADETRopinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalRopinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], [A174547]. … In 2008, the extended-release capsules of ropinirole were approved, allowing for less frequent dosing, therefore increased compliance, and offering a similar side effect profile and efficacy to previous
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: ROPINIROL AL 4 MG RET, ROPINIROL-NEURAX 4 MG