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Ximelagatran
go.drugbank.com/drugs/DB04898ApprovedWithdrawnIn 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue its distribution in countries … Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former.
Synonyms: ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin-1-yl]- 2-oxo-ethyl]amino]acetateNeratinib
go.drugbank.com/drugs/DB11828ApprovedInvestigationalNeratinib is currently under investigation for use in many other forms of cancer. … Neratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer.
Fluocortolone pivalate
go.drugbank.com/drugs/DB15777InvestigationalMixtures: ULTRALAN CRINALE SOLUSYON, 20 MLOxycodegol
go.drugbank.com/drugs/DB14146InvestigationalThe lack of abuse potential is believed to be due to the drug's slow rate of entry into brain, a unique characteristic compared to others in the opioid class [A33997, A34016]. … Nektar Therapeutics has filed an application for FDA approval of Loxicodegol for use in the treatment of chronic lower back pain [L3263]
Trodusquemine
go.drugbank.com/drugs/DB06333InvestigationalIt has demonstrated the ability to stimulate regeneration of heart and multiple other tissues in animal models [A176600]. … Trodusquemine, a spermine metabolite of cholesterol, is a naturally occurring aminosterol that inhibits protein tyrosine phosphatase 1B.
Pirenzepine
go.drugbank.com/drugs/DB00670ApprovedWithdrawnIt also potentiates the effect of other antiulcer agents such as cimetidine and ranitidine. It is generally well tolerated by patients. … It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence.
Resiquimod
go.drugbank.com/drugs/DB06530InvestigationalIt is also being studied to find out if adding it to a tumor vaccine improves the antitumor immune response. It is a type of imidazoquinoline and a type of immunomodulator. … A substance being studied in the treatment of some types of skin cancer. When put on the skin, resiquimod causes some immune cells to make certain chemicals that may help them kill tumor cells.
Trehalose-6-Phosphate
go.drugbank.com/drugs/DB02430ExperimentalCategories: Compounds used in a research, industrial, or household settingTricaprylin
go.drugbank.com/drugs/DB12176InvestigationalTricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease.
Categories: Compounds used in a research, industrial, or household settingDenopamine
go.drugbank.com/drugs/DB21277ExperimentalDenopamine is a small molecule drug. Denopamine has a monoisotopic molecular weight of 317.16 Da.
Categories: Compounds used in a research, industrial, or household setting