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Displaying results 31 - 40 of 308 in total
  1. Drug

    Nemolizumab

    go.drugbank.com/drugs/DB15252
    ApprovedInvestigational

    Nemolizumab is a humanized monoclonal modified immunoglobulin 2 (IgG2) antibody directed against interleukin-31 receptor alpha (IL-31RA),[L51159] which is an endogenous cytokine implicated in the pathophysiology

    Categories: Interleukin-31 Receptor alpha AntagonistSynonyms: Immunoglobulin G2, anti-(interleukin 31 receptor A) (human-Mus musculus monoclonal CIM331 γ-chain), disulfide with human-Mus musculus monoclonal CIM331 κ-chain, dimer, immunoglobulin G2-kappa, anti-[Homo sapiens IL31RA (interleukin 31 receptor subunit alpha)], humanized monoclonal antibody gamma2 heavy chain (1-445) [humanized VH (Homo sapiens IGHV1-2*02 (83.70%) -(IGHD
  2. Drug

    4A10

    go.drugbank.com/drugs/DB18292
    Experimental

    Synonyms: Anti-interleukin-7 Receptor α Monoclonal antibody
  3. Drug

    Prolactin G129R

    go.drugbank.com/drugs/DB18431
    Investigational

    Synonyms: Prolactin receptor antagonist (Prolactin G129R)
  4. Drug

    Sotatercept

    go.drugbank.com/drugs/DB12118
    ApprovedInvestigational

    It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain.

    Synonyms: ACTIVIN RECEPTOR TYPE IIA (SYNTHETIC HUMAN EXTRACELLULAR DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER, (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-
  5. Drug

    Prednisolone

    go.drugbank.com/drugs/DB00860
    ApprovedInvestigationalVet approved

    Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.

    Categories: Corticosteroid Hormone Receptor AgonistsProducts: PREDI K.B. TABLETS
  6. Drug

    Valziflocept

    go.drugbank.com/drugs/DB17728
    Investigational

    Synonyms: Recombinant human soluble fc-gamma receptor iib, Fc.gamma.riib receptor (human soluble extracellular fragment)
  7. Drug

    Sipavibart

    go.drugbank.com/drugs/DB21908
    ApprovedInvestigational

    [A274098] It works by binding to the SARS-CoV-2 spike protein receptor binding domain (RBD), neutralize the virus and preventing its entry into the host cell.

    Synonyms: Immunoglobulin G1-lambda, anti-[Homo sapiens severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody, Immunoglobulin G1 [242-phenylalanine,243-glutamic acid,260-tyrosine,262-threonine,264-glutamic acid,339-serine], anti-(severe acute respiratory syndrome coronavirus 2 spike glycoprotein receptor-binding
  8. Drug

    Betamethasone

    go.drugbank.com/drugs/DB00443
    ApprovedInvestigationalVet approved

    Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states inclu...

    Mixtures: COTA-KBCategories: Corticosteroid Hormone Receptor Agonists
  9. Drug

    PA3-17

    go.drugbank.com/drugs/DB18569
    Investigational

    PA3-17 is CD7-directed chimeric antigen receptor (CAR) T-cell therapy.

    Synonyms: Chimeric Antigen Receptor T Cells targeting CD7
  10. Drug

    B7-H3-specific chimeric antigen receptor T cells

    go.drugbank.com/drugs/DB18567
    Experimental

    Synonyms: B7-H3-specific chimeric antigen receptor T cells, Autologous chimeric antigen receptor (CAR) T cells targeting B7-H3