Search
Clobazam
go.drugbank.com/drugs/DB00349ApprovedIllicitInvestigational[A256963,A256868] This is likely because of clobazam's higher affinity to the α<sub>2</sub> subunit of the GABA<sub>A</sub> receptor, which mediates anxiolytic effects, than the α<sub>1</sub> subunit, … [A521,A522] In October 21, 2011, the FDA approved clobazam as an adjunctive treatment for seizures associated with Lennox-Gastaut syndrome in adults and children aged two years and older.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione, 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepineMirabegron
go.drugbank.com/drugs/DB08893ApprovedInvestigationalMirabegron has a comparatively favorable adverse effect profile as compared to other available treatment options, and its complementary mechanism to the antimuscarinics that came before it allows for its … [L32853] An extended-release granule formulation was subsequently granted approval in March 2021 for the treatment of pediatric patients with neurogenic detrusor overactivity.
Categories: Heterocyclic Compounds, 1-RingProducts: BETMIGA 25 MG UZATILMIŞ SALIMLI FILM TABLET , 10 TABLET, BETMIGA 50 MG UZATILMIŞ SALIMLI FILM TABLET , 10 TABLETTerbinafine
go.drugbank.com/drugs/DB00857ApprovedInvestigationalVet approved[A1279,A1281,L9068] Terbinafine hydrochloride was granted FDA approval on 30 December 1992.[L9064]
Synonyms: (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine, (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamineMixtures: M-FURO MANT % 0.1 + % 1 KREM, 20G, Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4%Apomorphine
go.drugbank.com/drugs/DB00714ApprovedInvestigational[A203597,A203618] Apomorphine was granted FDA approval on 20 April 2004.[L13919] … [A203618] Apomorphine has also been investigated as an emetic, a sedative, a treatment for alcoholism, and a treatment of other movement disorders.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol, (R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diolEphedrine
go.drugbank.com/drugs/DB01364ApprovedInvestigational[A193701,A193704,L12975] Ephedrine was granted a type 7 FDA Approval on 29 April 2016.[L12975] … Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with [pseudoephedrine].
Synonyms: (1R,2S)-1-Phenyl-1-hydroxy-2-methylaminopropane, L-erythro-2-(Methylamino)-1-phenylpropan-1-olMixtures: BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML, HEMORALGINE 40 GR POMADTenoxicam
go.drugbank.com/drugs/DB00469ApprovedInvestigationalTenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingProducts: TENOKTIL 20 MG KAPSÜL, 10 ADET, TILCOTIL 20 MG 10 SUPPZafirlukast
go.drugbank.com/drugs/DB00549ApprovedIt is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once daily.
Categories: Heterocyclic Compounds, 2-RingSynonyms: cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methylindole-5-carbamate, 4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamideUrsodeoxycholic acid
go.drugbank.com/drugs/DB01586ApprovedInvestigational[A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary biliary cirrhosis in 1996. … Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.
Synonyms: (3α,5β,7β)-3,7-dihydroxycholan-24-oic acid, 3alpha,7beta-Dihydroxy-5beta-cholan-24-oic acidProducts: URSOMED 300 MG KAPSÜL, 20 KAPSÜL, URSILON RETARD 225 MG KAPSÜL, 20 KAPSÜLMesalazine
go.drugbank.com/drugs/DB00244ApprovedInvestigationalAlthough demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent
Synonyms: m-Aminosalicylic acidProducts: KOLESA 250 MG SUPOZİTUVAR, 10 ADET, ASACOL 500 MG SUPOZITUVAR, 20 ADETCromoglicic acid
go.drugbank.com/drugs/DB01003ApprovedInvestigationalA chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic ...
Synonyms: 5-[3-(2-carboxy-4-oxo-4H-5-chromenyloxy)-2-hydroxypropoxy]-4-oxo-4H-2-chromenecarboxylic acidCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring