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Displaying results 4001 - 4010 of 10000 in total
  1. Drug

    Emricasan

    go.drugbank.com/drugs/DB05408
    Investigational

    Emricasan is the first caspase inhibitor tested in human which has received orphan drug status by FDA. … It is developed by Pfizer and made in such a way that it protects liver cells from excessive apoptosis.

  2. Drug

    TRX1

    go.drugbank.com/drugs/DB05863
    Experimental

    TRX1 is a humanized antibody that binds to the CD4 receptor found on a subset of T cells. … TRX1 is being developed for the potential treatment of autoimmune diseases in collaboration with Genentech, Inc. TolerRx is currently conducting a Phase I clinical study of TRX1 in the United Kingdom.

  3. Drug

    KW-7158

    go.drugbank.com/drugs/DB05498
    Experimental

    The therapeutic effects of KW-7158 in overactive bladder may be due to the activation of A-type K(+) channels which regulate afferent neuron excitability and firing properties in the dorsal root ganglion

  4. Drug

    Flortaucipir

    go.drugbank.com/drugs/DB15033
    Investigational

    Flortaucipir is under investigation in clinical trial NCT03507257 (Longitudinal Early-onset Alzheimer's Disease Study Protocol).

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Tedizolid

    go.drugbank.com/drugs/DB14569
    ApprovedInvestigational

    This product is currently available as both an oral tablet and as a powder for intravenous injection.[L11232] … [L11232, A199086, A199050] Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate (SIVEXTRO®).

  6. Drug

    Zolasartan

    go.drugbank.com/drugs/DB20140
    Experimental

    The usage of the INN stem '-sartan' in the name indicates that Zolasartan is a angiotensin II receptor antagonist, antihypertensive (non-peptidic).

    Categories: Agents Acting on the Renin-Angiotensin System
  7. Drug

    Methylselenocysteine

    go.drugbank.com/drugs/DB12697
    Investigational

    Methylselenocysteine has been used in trials studying the prevention of Prostate Carcinoma and No Evidence of Disease.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Seletracetam

    go.drugbank.com/drugs/DB05885
    Investigational

    Food and Drug Administration (FDA) investigated as treatment of epilepsy and partial epilepsy however its development had been put on hold in July 2007. … Seletracetam was in Phase II clinical trials under the supervision of the U.S.

  9. Drug

    Sulfobromophthalein

    go.drugbank.com/drugs/DB13215
    Experimental

    Sulfobromophthalein or otherwise called bromsulphthalein is used as a test of liver function in humans [A174970].

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Milveterol

    go.drugbank.com/drugs/DB05043
    Investigational

    GSK159797 ('797) is an inhaled, longer-acting Beta2 agonist developed for the treatment of respiratory disease such as asthma and COPD.