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Tolvaptan
go.drugbank.com/drugs/DB06212ApprovedInvestigationalTolvaptan is used to treat low blood sodium levels (hyponatremia) associated with various conditions like congestive heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormones (SIADH). FDA approved on May 19, 2009.
Iva axillaris pollen
go.drugbank.com/drugs/DB10764ApprovedIva axillaris pollen is the pollen of the Iva axillaris plant. Iva axillaris pollen is mainly used in allergenic testing.
Mixtures: Number Four Weed MixtureVevorisertib
go.drugbank.com/drugs/DB21481Investigational(MK-4440-001)). … Vevorisertib is under investigation in clinical trial NCT02761694 (Vevorisertib (ARQ 751) as a Single Agent or in Combination With Other Anti-Cancer Agents, in Solid Tumors With PIK3CA / AKT / PTEN Mutations
Emricasan
go.drugbank.com/drugs/DB05408InvestigationalEmricasan is the first caspase inhibitor tested in human which has received orphan drug status by FDA. It is developed by Pfizer and made in such a way that it protects liver cells from excessive apoptosis.
Allogeneic Cardiosphere-Derived Cells
go.drugbank.com/drugs/DB15744InvestigationalThey exert their effects by secreting exosomes: nanometer-sized, membrane-bound vesicles used for the purpose of cell-cell communication.
Penicillium italicum
go.drugbank.com/drugs/DB10811ApprovedPenicillium italicum is a fungus which can provoke allergic reactions. Penicillium italicum extract is used in allergenic testing.
Mixtures: Number Four Mold MixtureV-SARS
go.drugbank.com/drugs/DB15812Investigational[COVID-19 convalescent plasma] is currently being acquired from recovered COVID-19 patients and used as prophylaxis for the virus. … Immunitor Inc., the sponsor, is currently testing this oral vaccine for immunogenicity in 20 healthy volunteers in a Phase 1 clinical trial (NCT04380532).
Osoresnontrine
go.drugbank.com/drugs/DB16274InvestigationalOsoresnontrine is under investigation in clinical trial NCT02281773 (A Study to Investigate the Efficacy, Safety and Tolerability of Four Different Doses of BI 409306 Compared to Placebo Given for 12 Weeks
ReN001
go.drugbank.com/drugs/DB05236InvestigationalReN001 a strong candidate for one of the first cell-based IND applications to be submitted to the Food and Drug Administration in the United States for consideration for the treatment of stroke in humans … ReN001 is a clonal human neural stem cell line developed for clinical use in the treatment of stable disability after stroke.
Propantheline
go.drugbank.com/drugs/DB00782ApprovedA muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.
Categories: Drugs for Functional Gastrointestinal Disorders