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Citatuzumab Bogatox
go.drugbank.com/drugs/DB06072InvestigationalVB6-845 is a humanized antibody fragment targeting EpCAM fused with the deimmunized form of the cytotoxin Bouganin and is designed for systemic use against metastatic cancer. … VB6-845 has demonstrated effective cancer cell killing properties in pre-clinical tests.
Leronlimab
go.drugbank.com/drugs/DB05941InvestigationalLeronlimab, or PRO-140, is a human monoclonal antibody developed by CytoDyn.[L12684] It was first described in the literature in 2001. … [A3922] This antibody binds to CCR5, which may be useful in treating HIV, cancers, and severely ill COVID-19 patients.[A192846,A192858,L12684]
Categories: Experimental Unapproved Treatments for COVID-19Methdilazine
go.drugbank.com/drugs/DB00902ApprovedMethdilazine is a phenothiazine compound with antihistaminic activity. It is used in the treatment of various dermatoses to relieve pruritus.
Categories: Antihistamines for Systemic UseCefpirome
go.drugbank.com/drugs/DB13682ApprovedCefpirome is a β-lactam or cephalosporin.[A249055]
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseBarbexaclone
go.drugbank.com/drugs/DB09001ExperimentalWith this difference in potency in mind, other pharmacokinetic considerations such as dose titration, daily dosing, and optimal plasma concentration can be considered the same as for the equivalent amount … Barbexaclone, a salt compound of propylhexedrine and phenobarbital, is a potent antiepileptic. By weight, barbexaclone is 40% propylhexedrine and 60% phenobarbital.
Vatalanib
go.drugbank.com/drugs/DB04879InvestigationalVatalanib is under investigation for the treatment of solid tumors. … Vatalanib (PTK787/ZK-222584) is a new oral antiangiogenic molecule that inhibits all known vascular endothelial growth factor receptors.
Malic acid
go.drugbank.com/drugs/DB12751InvestigationalMalic acid has been used in trials studying the treatment of Xerostomia, Depression, and Hypertension.
Mixtures: Acerbine Salbe, AKE 1100 GLUKOZLU IV SOLOSYONU, 500 MLEpinastine
go.drugbank.com/drugs/DB00751ApprovedEpinastine is used for the prevention of itching associated with allergic conjunctivitis. … It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding
Mixtures: FLURINOL(R) D COMPRIMIDOS DE LIBERACION MODIFICADAApramycin
go.drugbank.com/drugs/DB04626InvestigationalVet approvedApramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted deoxystreptamine. It is not approved for use in humans. … Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria.
Synonyms: Nebramycin II, 4-O-((8R)-2-amino-8-O-(4-amino-4-deoxy-α-D-glucopyranosyl)-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranos-1-yl)-2-deoxy-D-streptamineVanoxerine
go.drugbank.com/drugs/DB03701Investigational[A248555] Vanoxerine is an investigational drug and has not been approved for therapeutic use. … Vanoxerine is a highly selective dopamine transporter antagonist. It was synthesized in the late 1970s and developed as a potential treatment for depression.