Epinastine is an H1 receptor antagonist used to prevent itching in allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1-...
- Mechanism
- Curator reviewed
Epinastine has a multiaction effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory chemical mediators from the blood vessel to halt progression of the allergic response.
- Primary indication
- For the prevention of itching associated with allergic conjunctivitis.Curator reviewed · 1 structured indication
- Formula / weight
- C16H15N3 · 249.3104 g/mol (avg)
- First approval
- United States, 2004
- Code names
- WAL 801 Cl
- Brand names
Resolves to
WHWZLSFABNNENI-UHFFFAOYSA-NSMILESNC1=NCC2N1C1=CC=CC=C1CC1=CC=CC=C21What you can answer from here — as of September 21, 2026
Which drugs share a target with Epinastine, and which of those have an active Phase 3 trial?
Create a free account or log in to explore the full data card.
Create Account