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Displaying results 4021 - 4030 of 10000 in total
  1. Drug

    Theofibrate

    go.drugbank.com/drugs/DB19587
    Experimental

    The usage of the INN stem '-fylline' in the name indicates that Theofibrate is a N-methylated xanthine derivative. … The usage of the INN stem '-fibrate' in the name indicates that Theofibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist.

    Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    Golotimod

    go.drugbank.com/drugs/DB05475
    Investigational

    SCV-07 has shown efficacy in treating various viral and bacterial infections. … In independent studies, treatment of tuberculosis with SCV-07 improved clearance of mycobacteria, improved cavity healing, improvements in immune parameters and reduced symptoms (fever, weakness, sweating

  3. Drug

    Thiamylal

    go.drugbank.com/drugs/DB01154
    ApprovedVet approved

    (From Martindale, The Extra Pharmacopoeia, 30th ed, p919)

  4. Drug

    Argatroban

    go.drugbank.com/drugs/DB00278
    ApprovedInvestigational

    Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT and prevent the formation of thrombi. … The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary

  5. Drug

    Tesevatinib

    go.drugbank.com/drugs/DB11973
    Investigational

    In addition, tesevatinib inhibits EphB4, an RTK that is highly expressed in many human tumors and plays a role in promoting angiogenesis. … In cell culture models, tesevatinib retains significant potency against mutant EGFRs that are resistant to current EGFR inhibitors.

  6. Drug

    DTS-201

    go.drugbank.com/drugs/DB06071
    Experimental

    It is activated in the tumor environment.

  7. Drug

    Rhein

    go.drugbank.com/drugs/DB13174
    Experimental

    Rhein is an anthraquinone metabolite of rheinanthrone and senna glycoside is present in many medicinal plants including Rheum palmatum, Cassia tora, Polygonum multiflorum, and Aloe barbadensis [A19247]

  8. Drug

    Pivhydrazine

    go.drugbank.com/drugs/DB09252
    ApprovedWithdrawn

    In 1960, it was widely used as an antidepressant agent but it is now discontinued.

  9. Drug

    Nitric acid

    go.drugbank.com/drugs/DB15995
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    LY2275796

    go.drugbank.com/drugs/DB05165
    Investigational

    LY2275796 targets eukaryotic initiation factor- 4E (eIF-4E), a protein involved in the translation of key growth and survival factors that drive tumor progression, angiogenesis and metastases.