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Displaying results 4041 - 4050 of 5897 in total
  1. Drug

    Stem-cell derived exosome vesicle products

    go.drugbank.com/drugs/DB15743
    Experimental

    Various bioactive molecules (including lipids, proteins, mRNAs, and tRNAs) are used to enrich exosomes. … Once secreted into extracellular fluid, exosomes are taken up by their target cells or carried to distant target sites.

  2. Drug

    MK-0354

    go.drugbank.com/drugs/DB05939
    Investigational

    It targets G protein-coupled receptor, or GPCR, that have the potential to regulate plasma lipid profiles, including HDL, or the good cholesterol, similar to the therapeutic action of niacin.

  3. Drug

    Diazepinomicin

    go.drugbank.com/drugs/DB12420
    Investigational

    It is a proprietary first-in-class small molecule with the potential to treat multiple solid tumours like the well known chemotherapeutics, doxorubicin and mitomycin C. … Discovered using Thallion’s DECIPHER technology, diazepinomicin has completed preclinical studies conducted by the National Cancer Institute and Thallion to establish safety and efficacy in animal and

    Synonyms: 4,6,8-trihydroxy-10-(3,7,11-trimethyldodeca-2,6,10-trienyl)-5,10-dihydrodibenzo(b,e)(1,4)diazepin-11-one
  4. Drug

    Mebenil

    go.drugbank.com/drugs/DB14728
    Experimental

    An obsolete fungicide used to control various pathogens on cereals and seed potatoes.

    Synonyms: o-Toluanilide, o-Methylbenzanilide
  5. Drug

    D-Cysteine

    go.drugbank.com/drugs/DB03201
    Experimental

    A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.

  6. Drug

    Lobeline

    go.drugbank.com/drugs/DB05137
    Investigational

    An alkaloid that has actions similar to nicotine on nicotinic cholinergic receptors but is less potent.

  7. Drug

    CYC116

    go.drugbank.com/drugs/DB05198
    Investigational

    Cyclacel's small molecule investigational drug, CYC116, is the third orally-available Cyclacel drug to enter development, which demonstrated anticancer activity with a mechanism consistent with inhibition

  8. Drug

    Tenamfetamine

    go.drugbank.com/drugs/DB01509
    IllicitInvestigational

    An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for...

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  9. Drug

    Budiodarone

    go.drugbank.com/drugs/DB05519
    Investigational

    Budiodarone (ATI-2042) is an antiarrhythmic related to amiodarone that is currently being studied in clinical trials.

  10. Drug

    Uridine 5'-triphosphate

    go.drugbank.com/drugs/DB04005
    Investigational

    A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.