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AT-GTX-502
go.drugbank.com/drugs/DB17001ExperimentalAT-GTX-502 is an experimental, one-time gene therapy that uses AAV9 to deliver a functional copy of CLN3.
Categories: Non-Replicating Recombinant, Self-Complementary Adeno-Associated Virus Serotype 9 Containing the Human CLN3 GeneTreosulfan
go.drugbank.com/drugs/DB11678ApprovedInvestigationalTreosulfan is a prodrug alternative to [busulfan] for myeloablative conditioning prior to hematopoietic stem cell transplantation. … [L52245] It was approved by the EMA in June 2019[L16965] and by the FDA in January 2025 for use in combination with [fludarabine].[L52575]
Synonyms: L-threitol-1,4-dimethanesulfonateCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsPalivizumab
go.drugbank.com/drugs/DB00110ApprovedInvestigationalThe human heavy chain sequence was derived from the constant domains of human IgG1 and the variable framework regions of the VH genes Cor (1) and Cess (2). … Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV).
Categories: Respiratory Syncytial Virus Anti-F Protein Monoclonal AntibodyProducts: SYNAGIS 100 MG/1 ML IM ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON,1 ADET, SYNAGIS® 50 MGTrimethadione
go.drugbank.com/drugs/DB00347ApprovedWithdrawnAn anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingCarfilzomib
go.drugbank.com/drugs/DB08889ApprovedInvestigationalFDA approved carfilzomib in July 2012 for the treatment of adults with relapsed or refractory multiple myeloma as monotherapy or combination therapy.[L39392] … Carfilzomib is an injectable antineoplastic agent (IV only). Chemically, it is a modified tetrapeptidyl epoxide and an analog of epoxomicin. It is also a selective proteasome inhibitor.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsProducts: KYPROLIS®, KARFIB®Tilbroquinol
go.drugbank.com/drugs/DB13222ApprovedIn Morocco, the drug has been limited to use in the treatment of intestinal amoebiasis. … Tilbroquinol was approved in France, Morocco, and Saudi Arabia but it has been withdrawn in France and Saudi Arabia markets mainly due to its hepatotoxicity risk outweighing the drug benefit [L5467].
Categories: Heterocyclic Compounds, 2-RingMidodrine
go.drugbank.com/drugs/DB00211ApprovedInvestigationalAn ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Categories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor AgonistsSynonyms: 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol, (±)-2-amino-N-(β-hydroxy-2,5-dimethoxyphenethyl)acetamideAdenosine phosphate
go.drugbank.com/drugs/DB00131ApprovedInvestigationalNutraceuticalWithdrawnAdenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. … Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.[L43937]
Categories: Heterocyclic Compounds, 2-RingSynonyms: Fosfato de adenosina, Adenosine-5'PIoxilan
go.drugbank.com/drugs/DB09135ApprovedWithdrawnIoxilan is a tri-iodinated diagnostic contrast agent. … Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant
Categories: X-Ray Contrast Activity, X-Ray Contrast Media, IodinatedSynonyms: N-(2,3-dihydroxypropyl)-N’-(2- hydroxyethyl)-5-[N-(2,3-dihydroxypropyl) acetamido]-2,4,6-triiodoisophthal-amideApis mellifera venom
go.drugbank.com/drugs/DB10955ApprovedApis mellifera venom is an extract of Apis mellifera venom. Apis mellifera venom is used in allergenic testing.
Mixtures: ALUTARD SQ Bienengift Injektionssuspension (Anfangsbehandlung) (100 SQ E/ml, 1.000 SQ E/ml, 10.000 SQ E/ml und 100.000 SQ E/ml), ALUTARD SQ Bienengift Injektionssuspension (Anfangsbehandlung) (100 SQ E/ml, 1.000 SQ E/ml, 10.000 SQ E/ml und 100.000 SQ E/ml)Products: ALUTARD SQ Bienengift 100.000 SQ-E/ml Injektionssuspension (Fortsetzungsbehandlung)