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Fenbufen
go.drugbank.com/drugs/DB08981ApprovedIt can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. … Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis.
Synonyms: 4-(4-Biphenylyl)-4-oxobutyric acid, 3-(4-Phenylbenzoyl)propionic acidCategories: Non COX-2 selective NSAIDSTalazoparib
go.drugbank.com/drugs/DB11760ApprovedInvestigational[L47301] Talazoparib is currently used in the treatment of BRCA-mutated breast cancer and HRR-mutated prostate cancer.[L47236, L47301, L47306] … [L47236] Developed by Pfizer, talazoparib was first approved by the FDA in October 2018 [A260346] and by the EMA in June 2019.[L47296] It was approved by Health Canada in September 2020.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein substratesPegunigalsidase alfa
go.drugbank.com/drugs/DB14992ApprovedInvestigational[A259347,A259352] In May 2023, the EMA granted marketing authorization to pegunigalsidase alfa in the European Union (EU) for the treatment of adult patients with Fabry disease. … to a different glycosylation pattern.
Carphenazine
go.drugbank.com/drugs/DB01038ApprovedWithdrawnCarphenazine is an antipsychotic drug, used in hospitalized patients in the management of chronic schizophrenic psychoses.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsPalivizumab
go.drugbank.com/drugs/DB00110ApprovedInvestigationalThe human heavy chain sequence was derived from the constant domains of human IgG1 and the variable framework regions of the VH genes Cor (1) and Cess (2). … Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV).
Categories: Respiratory Syncytial Virus Anti-F Protein Monoclonal AntibodyProducts: SYNAGIS 100 MG/1 ML IM ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON,1 ADET, SYNAGIS® 50 MGTreosulfan
go.drugbank.com/drugs/DB11678ApprovedInvestigationalTreosulfan is a prodrug alternative to [busulfan] for myeloablative conditioning prior to hematopoietic stem cell transplantation. … [L52245] It was approved by the EMA in June 2019[L16965] and by the FDA in January 2025 for use in combination with [fludarabine].[L52575]
Synonyms: L-threitol-1,4-dimethanesulfonateCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsTilbroquinol
go.drugbank.com/drugs/DB13222ApprovedIn Morocco, the drug has been limited to use in the treatment of intestinal amoebiasis. … Tilbroquinol was approved in France, Morocco, and Saudi Arabia but it has been withdrawn in France and Saudi Arabia markets mainly due to its hepatotoxicity risk outweighing the drug benefit [L5467].
Categories: Heterocyclic Compounds, 2-RingMidodrine
go.drugbank.com/drugs/DB00211ApprovedInvestigationalAn ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Categories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor AgonistsSynonyms: 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol, (±)-2-amino-N-(β-hydroxy-2,5-dimethoxyphenethyl)acetamideStarch, corn
go.drugbank.com/drugs/DB11599ApprovedInvestigationalNutraceuticalCorn starch refers to the starch extracted from the corn grain that is commonly used as a food ingredient and chemical additive. … Starch is any of a group of polysaccharides of the general formula (C6-H10-O5)n, composed of a long-chain polymer of glucose in the form of amylose and amylopectin.
Categories: Compounds used in a research, industrial, or household settingAldesleukin
go.drugbank.com/drugs/DB00041ApprovedInvestigationalThis recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2.
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: 125-L-Serine-2-133-interleukin 2, 125-L-serine-2-133-interleukin 2 (human reduced)