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Milbemycin oxime
go.drugbank.com/drugs/DB11531ExperimentalVet approvedMixtures: Nexgard Spectra 9mg/2mg Chewable Tablets for Dogs 2-3.5kg, Nexgard Spectra 38mg/8mg Chewable Tablets for Dogs >7.5-15kgMycobacterium w. Vaccine
go.drugbank.com/drugs/DB15798InvestigationalIt has protective efficacy against M. tuberculosis and M. leprae. As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials. … As an immunotherapy, M.w is used against leprosy; the compound also shares antigens with M. tuberculosis.
Categories: Complex MixturesZileuton
go.drugbank.com/drugs/DB00744ApprovedWithdrawnBoth the R(+) and S(-) enantiomers are pharmacologically active as 5-lipoxygenase inhibitors in in vitro systems. The immediate release tablet of Zileuton has been withdrawn from the US market. … These effects contribute to inflammation, edema, mucus secretion, and bronchoconstriction in the airways of asthmatic patients.
Synonyms: N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea, N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyureaN,N'-diphenyl-1,4-phenylenediamine
go.drugbank.com/drugs/DB14192ApprovedSynonyms: N,N'-diphenyl-1,4-phenylenediamineCategories: Compounds used in a research, industrial, or household settingBentonite
go.drugbank.com/drugs/DB11306ApprovedWithdrawnCategories: Compounds used in a research, industrial, or household settingPractolol
go.drugbank.com/drugs/DB01297ApprovedA beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.
Synonyms: N-(4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)acetamideSulfacytine
go.drugbank.com/drugs/DB01298ApprovedHigh levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. … The inhibited reaction is necessary in these organisms for the synthesis of folic acid.
Synonyms: 1-ethyl-N-sulfanilylcytosineDarolutamide
go.drugbank.com/drugs/DB12941ApprovedInvestigationalThis condition occurs in the majority of patients with advanced prostate cancer who have been treated with androgen receptor antagonists. … [A189054,A189063] Darolutamide was developed by Bayer HealthCare Pharmaceuticals Inc. and approved by the FDA on July 30th, 2019.[L10887]
Amlexanox
go.drugbank.com/drugs/DB01025ApprovedWithdrawnRecurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of the general population. … Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis.
Vaborbactam
go.drugbank.com/drugs/DB12107ApprovedInvestigational[A32053] It has been used in trials investigating the treatment of bacterial infections in subjects with varying degrees of renal insufficiency. … In August 2017, a combination antibacterial therapy under the market name Vabomere was approved by the FDA for the treatment of adult patients with complicated urinary tract infections (cUTI).