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Methylpropylpropanediol dinitrate
go.drugbank.com/drugs/DB13408ExperimentalCategories: Vasodilators Used in Cardiac DiseasesAZD-8330
go.drugbank.com/drugs/DB06061InvestigationalAZD-8330 is a potent, selective, orally active MEK inhibitor that blocks signal transduction pathways implicated in cancer cell proliferation and survival. … AZD-8330 has shown tumor suppressive activity in multiple preclinical models of human cancer including melanoma, pancreatic, colon, lung, and breast cancers.
Spermine
go.drugbank.com/drugs/DB00127InvestigationalNutraceuticalFound in various tissues and organisms, it often acts as an essential growth factor in some bacterial species. … Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.
Synonyms: N,N'-Bis(3-aminopropyl)-1,4-butanediamineCHF 4227
go.drugbank.com/drugs/DB05882ExperimentalThe compound has a high receptor affinity and has shown promising efficacy in the prevention of bone loss in animal models of osteoporosis. … Additionally, the compound has shown no uterotrophic activity suggesting a potential therapeutic advantage over drugs normally used in postmenopausal therapy.
Influenza B virus B/Michigan/01/2021 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB16917ApprovedThese vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in an immunological defense against future exposure to the virus, or "antigen … Inactivated viruses cannot replicate and thus cannot cause disease from infection, even in immunocompromised individuals.
rhIGFBP-3
go.drugbank.com/drugs/DB05897InvestigationalrhIGFBP-3 (recombinant human insulin-like growth factor binding protein-3) is Insmed’s proprietary anti-cancer compound that has demonstrated significant decreases in cancerous growth in several models
Detomidine
go.drugbank.com/drugs/DB11556InvestigationalVet approvedCurrently, it is only approved by the FDA for use in horses but has been studied for use in other large animals. … Detomidine is an α2-adrenergic agonist that is used as a horse sedative. Normally, it is administered in the salt form, detomidine hydrochloride.
Tirofiban
go.drugbank.com/drugs/DB00775ApprovedInvestigationalTirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide reversible antagonist of the platelet glyc...
Synonyms: N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosineTechnetium Tc-99m red blood cells
go.drugbank.com/drugs/DB09493ApprovedWithdrawnAutologous red blood cells are radiolabeled with sodium pertechnetate Tc 99m in the reaction vial. … It is clinically useful in early detection and localization of bleeding sites, and preoperative diagnosis of hemangioma [A32178, A32179].
Dextromoramide
go.drugbank.com/drugs/DB01529ExperimentalIllicitAn opioid analgesic structurally related to methadone and used in the treatment of severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1070)