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Barnidipine
go.drugbank.com/drugs/DB09227InvestigationalThe active component is composed of a single optical isomer (*3'S, 4S* configuration), which is the most potent and longest-acting of the four enantiomers [A31567]. … Used in the treatment of hypertension, barnidipine displays high affinity for the calcium channels of the smooth muscle cells in the vascular wall [L1131] and selectivity against cardiovascular L-type
Iroxanadine
go.drugbank.com/drugs/DB05444ExperimentalBRX-235 also causes translocation of calcium-dependent protein kinase C isoform to membranes. … It induces phosphorylation of p38 SAPK, which plays an important role in EC homeostasis. endothelial cell (EC).
Eniluracil
go.drugbank.com/drugs/DB03516Investigationalbasal cell cancer of the skin. … Eniluracil, which was previously under development by GlaxoSmithKline (GSK), is being developed by Adherex to enhance the therapeutic value and effectiveness of 5-fluorouracil (5-FU), one of the world’
Haloprogin
go.drugbank.com/drugs/DB00793ApprovedWithdrawnHaloprogin is used as a topical ointment or cream in the treatment of Tinea infections. … The mechanism of action is unknown, but it is thought to be via inhibition of oxygen uptake and disruption of yeast membrane structure and function.
Perospirone
go.drugbank.com/drugs/DB08922InvestigationalPerospirone is an atypical or second-generation antipsychotic of the azapirone family that antagonizes serotonin 5HT2A receptors and dopamine D2 receptors. … Dainippon Sumitomo Pharma developed perospirone in Japan in 2001 for the treatment of acute schizophrenia and bipolar mania as well as chronic schizophrenia.
Siroheme
go.drugbank.com/drugs/DB02832ExperimentalCategories: Heterocyclic Compounds with 4 or More RingsFerroheme C
go.drugbank.com/drugs/DB03317ExperimentalCategories: Heterocyclic Compounds with 4 or More Rings