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Affitope AD01
go.drugbank.com/drugs/DB06086InvestigationalAD01 is a short peptide (7 amino acids in length) that induces Aß-targeting antibodies, therefore lowering Aß aggregates. … Affitope AD01 is an investigational drug developed for immunization to treat Alzheimer's Disease.
Pegaptanib
go.drugbank.com/drugs/DB04895ApprovedWithdrawnPegaptanib is a polynucleotide aptamer. Pegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and vessel permeability. … Pegaptanib was granted FDA approval on 17 September 2004.[L17903]
Categories: Vascular Endothelial Growth Factor ASqualamine
go.drugbank.com/drugs/DB06461InvestigationalCategories: Compounds used in a research, industrial, or household settingNBI-6024
go.drugbank.com/drugs/DB05819InvestigationalNBI-6024 is an altered peptide ligand that is designed to cause an immune response which result in preservation of beta-cell function and endogenous insulin production.
Hydroxytyrosol
go.drugbank.com/drugs/DB12771InvestigationalHydroxytyrosol has been used in trials studying the prevention of Breast Cancer.
Categories: Compounds used in a research, industrial, or household settingBicalutamide
go.drugbank.com/drugs/DB01128ApprovedInvestigationalBicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsProducts: BICALUTAMIDE EG, BICALUTAMIDE EG STADAAmilomotide
go.drugbank.com/drugs/DB05150InvestigationalCAD106 is an immunotherapeutic product in development for the treatment of Alzheimer's disease. … It is designed to induce antibodies against the beta-amyloid-protein that inhibit the formation of plaques in the brain of Alzheimer's disease patients.
Avapritinib
go.drugbank.com/drugs/DB15233ApprovedInvestigationalAvapritinib was granted FDA approval on 9 January 2020 [L40363] and EMA approval on 24 September 2020.[L41464] … [A189339,L40363] It is one of the first medications available for the treatment of multidrug resistant cancers.[A189327] Avapritinib shares a similar mechanism with [ripretinib].
Categories: MATE 2-K Inhibitors, MATE 1 InhibitorsCortisone acetate
go.drugbank.com/drugs/DB01380ApprovedInvestigationalCortisone acetate was first isolate in 1935 and became more widely researched in 1949. … [A226295] Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory conditions such as endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory
Categories: P-glycoprotein inducers, P-glycoprotein substratesTerconazole
go.drugbank.com/drugs/DB00251ApprovedTerconazole is an anti-fungal drug that is mainly used to treat vaginal yeast infections (or vaginal candidiasis). It is classified as a _triazole ketal derivative_. … [FDA label] This drug is available in cream and suppository forms and both have demonstrated high levels of safety, efficacy, and tolerability in clinical trials.
Mixtures: TEREX-3, Terazol 3 Dual PakCategories: Heterocyclic Compounds, 1-Ring