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S-3304
go.drugbank.com/drugs/DB12149InvestigationalS-3304 has been used in trials studying the treatment of Lung Cancer, Solid Tumors, Non Small Cell Lung Cancer, Stage IIIB Non Small Cell Lung Cancer, and Stage IIIA Non Small Cell Lung Cancer, among others
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingReparixin
go.drugbank.com/drugs/DB12614Investigational1, and Pancreatic Islet Transplantation in Type 1 Diabetes Mellitus. … Reparixin has been used in trials studying the treatment and prevention of Breast Cancer, Metastatic Breast Cancer, Pancreatectomy for Chronic Pancreatitis, Islet Transplantation in Diabetes Mellitus Type
Onapristone
go.drugbank.com/drugs/DB12637InvestigationalTumor: Max 1 Line of Prior Chemotherapy, no Prior Hormone Therapy. … Onapristone has been used in trials studying the treatment of Prostate Cancer, Recurrent Prostate Cancer, Metastatic Prostate Cancer, Androgen-independent Prostate Cancer, and Progesterone Receptor Positive
XL765
go.drugbank.com/drugs/DB05241InvestigationalXL765 is an orally available small molecule that has been shown in preclinical studies to selectively inhibit the activity of phosphoinositide-3 kinase (PI3K) and mammalian target of rapamycin (mTOR).
Categories: Heterocyclic Compounds, 2-Ring, Phosphatidylinositol 3-Kinases, antagonists & inhibitorsNaquotinib
go.drugbank.com/drugs/DB12036InvestigationalNaquotinib has been used in trials studying the treatment of Solid Tumors, Non-small Cell Lung Cancer, Non-Small-Cell Lung Cancer (NSCLC), Epidermal Growth Factor Receptor Mutations, and Epidermal Growth … Factor Receptor (EGFR) Mutations, among others.
Categories: Heterocyclic Compounds, 1-RingEGT-201
go.drugbank.com/drugs/DB17648ExperimentalEGT-201 is an adeno-associated viral vector serotype 9 (AAV9) vector-based gene therapy consisting of the alpha-N-acetyglucosaminidase (NAGLU) transgene. … Developed by Esteve Pharmaceuticals, it is being investigated for Sanfilippo syndrome type B.[L45939]
Terevalefim
go.drugbank.com/drugs/DB16397InvestigationalTerevalefim is under investigation in clinical trial NCT02474667 (Reduce the Severity of DGF in Recipients of a Deceased Donor Kidney).
Categories: Heterocyclic Compounds, 1-RingCenisertib
go.drugbank.com/drugs/DB06347InvestigationalCenisertib is an aurora kinase inhibitor.
Categories: Heterocyclic Compounds, 1-RingElacytarabine
go.drugbank.com/drugs/DB05494InvestigationalElacytarabine is a fatty acid derivative of [cytarabine], an approved cytotoxic cancer drug. Cytarabine has limitations such as minimal uptake in solid tumours and is only used to treat leukaemia. … Elacytarabine is a patented new chemical entity of the nucleoside analog class, with improved biological properties and the potential to treat solid tumours such as non-small cell lung cancer, malignant
Categories: Heterocyclic Compounds, 1-Ring