Search

Displaying results 401 - 410 of 10000 in total
  1. Drug

    Levoleucovorin

    go.drugbank.com/drugs/DB11596
    ApprovedInvestigational

    Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. … As methotrexate functions as a DHFR inhibitor to prevent DNA synthesis in rapidly dividing cells, it also prevents the formation of DHF and THF.

    Categories: Vitamin B Complex, Heterocyclic Compounds, 2-RingSynonyms: (S)-Leucovorin, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
  2. Drug

    Hydrastine

    go.drugbank.com/drugs/DB19354
    Experimental

    Synonyms: (s)-6,7-dimethoxy-3-(r)-(6-methyl-5,6,7,8-tetrahydro-(1,3)dioxolo(4,5-g)isoquinolin-5-yl)isobenzofuran-1(3h)-one, Phthalide (s)-6,7-dimethoxy-3-(r)-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Substrates
  3. Drug

    CVac

    go.drugbank.com/drugs/DB17351
    Experimental

    Synonyms: Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase) coupled to oxidized polymannose
  4. Drug

    Oxfenicine

    go.drugbank.com/drugs/DB04291
    Experimental

    Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).

    Synonyms: (S)-(4-hydroxyphenyl)glycine, L-2-(p-hydroxyphenyl)glycineCategories: Carnitine O-Palmitoyltransferase, antagonists & inhibitors
  5. Drug

    Cyclo(prolylglycyl)

    go.drugbank.com/drugs/DB04541
    Investigational

    NA-831 (Traneurocin), is under investigation in two clinical trials: NCT03538522 (completed, for mild cognitive impairment and Alzheimer’s disease) and NCT04452565 (unknown status, combination therapy

    Synonyms: (S)-Hexahydropyrrolo(1,2-a)pyrazine-1,4-dione-4-17O, Cyclo(pro-O-gly)
  6. Drug

    Modufolin

    go.drugbank.com/drugs/DB12676
    Investigational

    Modufolin is under investigation for the treatment of Osteosarcoma.

    Synonyms: (6R,S)5,10-methylene-tetrahydrofolic acid, D-N5,N10-METHYLENE-L-TETRAHYDROFOLIC ACID
  7. Drug

    KH064

    go.drugbank.com/drugs/DB04287
    Experimental

    Synonyms: (S)-5-(4-Benzyloxy-phenyl)-4-(7-phenyl-heptanoylamino)-pentanoic acid, 5-(4-Benzyloxyphenyl)-4S-(7-phenylheptanoylamino)pentanoic acid
  8. Drug

    YK-4-279

    go.drugbank.com/drugs/DB17428
    Experimental

    Synonyms: (S)-YK-4-279, 4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-oneCategories: Heterocyclic Compounds, 2-Ring
  9. Drug

    APT-101

    go.drugbank.com/drugs/DB18003
    Experimental

    Synonyms: (S)-3-(1-Cyclopentyl-5-(2-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxamido)-5-(3,3-difluoropiperidin-1-yl)pentanoic acid
  10. Drug

    Glycerol Tribenzoate

    go.drugbank.com/drugs/DB16930
    Investigational

    Synonyms: Benzoflex s 404