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Remibrutinib
go.drugbank.com/drugs/DB16852ApprovedInvestigationalRemibrutinib is a selective Bruton's tyrosine kinase inhibitor. The FDA approved remibrutinib on September 30, 2025 as the only oral, targeted treatment for chronic spontaneous urticaria. … [L54101] Bruton's tyrosine kinase plays a role in B cell receptor and Fc receptor signalling, releasing histamine and pro-inflammatory mediators.
Lotiglipron
go.drugbank.com/drugs/DB21631InvestigationalLotiglipron has a monoisotopic molecular weight of 574.2 Da. … Lotiglipron is a small molecule drug. The usage of the INN stem '-glipron' in the name indicates that Lotiglipron is a glucagon-like peptide 1 receptor (GLPIR) agonist.
Tocotrienol
go.drugbank.com/drugs/DB12647InvestigationalTocotrienol has been investigated for the treatment of Cholesterol Lowering.
Mixtures: NHF Tocotrienol E Plus Vitamin D3 SoftgelCategories: Compounds used in a research, industrial, or household settingMontmorillonite
go.drugbank.com/drugs/DB13654InvestigationalMixtures: Dr. SEED Teatree and Lime Vegan No-sebum Cool Anti HairlossShampooCategories: Compounds used in a research, industrial, or household settingRusfertide
go.drugbank.com/drugs/DB17724ApprovedInvestigational[L64098] The FDA approved rusfertide on August 28, 2026 for the treatment of erythrocytosis in adults with polycythemia vera, a blood cancer. … Rusfertide is a hepcidin mimetic used to treat erythrocytosis in adults with polycythemia vera.
TGAAC94
go.drugbank.com/drugs/DB06175InvestigationalThe Health Recombinant DNA Advisory Committee (RAC) concluded that a possible role of the gene transfer in this clinical course could not definitively be excluded due to the lack of data. [A264038] … tgAAC94 is a recombinant adeno-associated virus serotype 2 (AAV2) vector containing the cDNA for a human tumor necrosis factor receptor (TNFR)-immunoglobulin (IgG1) Fc fusion (TNFR:Fc) gene.
Strontium chloride Sr-89
go.drugbank.com/drugs/DB09498ApprovedStrontium chloride (Sr-89), initially FDA-approved in 1993, is used as a paliative therapeutic option to help relieve the pain from bone metastases. … [A31264] Bone metastases is a common and severe complication presented in advanced stages of the disease.
Deoxycholic acid
go.drugbank.com/drugs/DB03619ApprovedInvestigationalDeoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that … In April 2015, deoxycholic acid was approved by the FDA for the treatment submental fat to improve aesthetic appearance and reduce facial fullness or convexity.
Alosetron
go.drugbank.com/drugs/DB00969ApprovedWithdrawnIn June 2002, the FDA approved a supplemental new drug application allowing the remarketing of the drug under restricted conditions of use. … Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women.
Buclizine
go.drugbank.com/drugs/DB00354ApprovedIt was manufactured by Stuart Pharms and initially approved by the FDA in 1957.