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Displaying results 4111 - 4120 of 10000 in total
  1. Drug

    Diacerein

    go.drugbank.com/drugs/DB11994
    ApprovedInvestigationalWithdrawn

    Diacerein is a prodrug which is metabolized to rhein. … It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including severe diarrhea [L780].

  2. Drug

    Friulimicin B

    go.drugbank.com/drugs/DB06087
    Investigational

    It shows strong cidal activity against a number of Gram-positive pathogens which commonly cause serious infections in hospital patients and which are becoming more routinely acquired in the community. … Friulimicin B is a naturally occurring antibiotic produced by a micro-organism, *Actinoplanes friuliensis*.

  3. Drug

    Resveratrol

    go.drugbank.com/drugs/DB02709
    Investigational

    Resveratrol (3,5,4'-trihydroxystilbene) is a polyphenolic phytoalexin. It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase. … It exists as cis-(Z) and trans-(E) isomers. The trans- form can undergo isomerisation to the cis- form when heated or exposed to ultraviolet irradiation. In a 2004 issue of Science, Dr.

    Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    Nefiracetam

    go.drugbank.com/drugs/DB13082
    Investigational

    Nefiracetam has been used in trials studying the treatment of Alzheimer's Disease.

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    DG051

    go.drugbank.com/drugs/DB05177
    Experimental

    DG051 is a novel small-molecule inhibitor of leukotriene A4 hydrolase (LTA4H), the protein made by one of the genes in the leukotriene pathway that has been shown to link to risk of heart attack. … DG051 is designed to decrease risk of heart attack by decreasing the production of leukotriene B4 (LTB4), an end product of the leukotriene pathway and a potent promoter of inflammation.

  6. Drug

    Candesartan

    go.drugbank.com/drugs/DB13919
    Investigational

    Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of [candesartan cilexetil].

    Categories: Angiotensin II receptor antagonists, Angiotensin II Type 2 Receptor BlockersProducts: CANDESARTAN AL 4 MG TABL, CANDESARTAN AL 8 MG TABL
  7. Drug

    Lasalocid

    go.drugbank.com/drugs/DB11423
    ExperimentalVet approved

    Lasalocid is an agent that presents antibacterial and coccidiostat activities. It is produced by strains of _Streptomyces lasaliensis_.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Eliprodil

    go.drugbank.com/drugs/DB12869
    Investigational

    Eliprodil has been used in trials studying the treatment of Parkinson Disease and Movement Disorders.

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    AT9283

    go.drugbank.com/drugs/DB05169
    Investigational

    AT9283 is an aurora Kinase inhibitor developed by Astex Therapeutics for the treatment of cancer. … It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid.

  10. Drug

    VIT-100

    go.drugbank.com/drugs/DB05865
    Experimental

    In preclinical studies, companyl has shown that VIT-100 inhibits the growth of cells taken from multiple keloid biopsies as compared to the same keloidal cells treated with a control. … It is believed that similar effects would be seen in cells isolated from hypertrophic scars.