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Displaying results 4121 - 4130 of 10000 in total
  1. Drug

    Pipamperone

    go.drugbank.com/drugs/DB09286
    Investigational

    Pipamperone is a typical antipsychotic of the _butyrophenone_ family used in the treatment of schizophrenia. … Interestingly, when [risperidone] was created, Janssen suggested it was a more potent version of pipamperone.

    Categories: Dopamine D2 Receptor Antagonists, Serotonin Receptor Antagonists
  2. Drug

    SR-9011

    go.drugbank.com/drugs/DB14014
    Experimental

    SR-9011 is a REV-ERB agonist. … SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl-
  3. Drug

    Racivir

    go.drugbank.com/drugs/DB12753
    Investigational

    Racivir is a 50:50 mixture of [emtricitabine] and its positive enantiomer. Racivir has been used in trials studying the prevention of HIV Infections.

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    TC-5231

    go.drugbank.com/drugs/DB05333
    Experimental

    TC-5231 is a small molecule that has been under investigation as an oral treatment for ADHD (Attention Deficit/Hyperactivity Disorder). … TC-5231 is mecamylamine hydrochloride, the active ingredient in FDA-approved product, Inversine, but in a lower dose than Inversine.

  5. Drug

    SB-269970

    go.drugbank.com/drugs/DB13988
    Experimental

    In the studies performed with this agent, it has been suggested that SB-269970 acts either as a selective antagonist or inverse agonist of the serotonin receptor 7 (5-HT7).[A31816,A31817]

  6. Drug

    BBM-H803

    go.drugbank.com/drugs/DB17700
    Investigational

    BBM-H803 is a recombinant adeno-associated virus (AAV) based gene therapy drug for hemophilia A developed and manufactured by Belief BioMed.

  7. Drug

    SIG-007

    go.drugbank.com/drugs/DB17710
    Experimental

    SIG-007 is a gene therapy that consists of cells that are genetically modified with a non-viral vector to express human alpha-galactosidase A. … Developed by Sigilon Therapeutics, t is being investigated for the treatment of Fabry Disease.[L46153]

  8. Drug

    Alethine

    go.drugbank.com/drugs/DB05800
    Investigational

    It belongs to a family of chemicals called disulfides. It is a low molecular weight disulfide that has been shown to exhibit in vivo antitumor activity in murine myeloma and melanoma models.

  9. Drug

    CERE-120

    go.drugbank.com/drugs/DB05637
    Investigational

    CERE-120 is an investigational drug consisting of an adeno-associated virus (AAV) that was engineered to carry the human gene for neurturin, a neurotrophic (growth) factor.

    Synonyms: adeno-associated virus serotype 2 [AAV2]-neurturin [NTN]
  10. Target

    Zinc transporter SLC39A7

    go.drugbank.com/bio_entities/BE0009893
    TransporterHumans

    Has an essential role in B cell development and is required for proper B cell receptor signaling (PubMed:30718914).

    Synonyms: Really interesting new gene 5 protein