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Displaying results 4161 - 4170 of 10000 in total
  1. Drug

    PTI-801

    go.drugbank.com/drugs/DB05300
    Investigational

    PTI-801 can minimize the opioid tolerance, dependence or addiction that is often associated with repeat use of oxycodone. … It is a combination of oxycodone with ultralow-dose naltrexone, an opioid antagonist.

  2. Drug

    Aprepitant

    go.drugbank.com/drugs/DB00673
    ApprovedInvestigational

    Aprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting … Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors.

    Categories: Neurokinin-1 Receptor Antagonists, Substance P/Neurokinin-1 Receptor Antagonist
  3. Drug

    Tideglusib

    go.drugbank.com/drugs/DB12129
    ApprovedInvestigationalWithdrawn

    It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3). … [A31601] Tideglusib is being developed by the Spanish pharmaceutic company Zeltia group and its current status is withdrawn for the treatment of Alzheimer's disease as of 2012.

  4. Drug

    Fendiline

    go.drugbank.com/drugs/DB08980
    ApprovedWithdrawn

    Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. … Fendiline is non-selective.

  5. Drug

    UCB-1184197

    go.drugbank.com/drugs/DB05092
    Investigational

    CDP323 is an antagonist of the _vascular cell adhesion molecule 1_ (VCAM-1) binding to alpha4-integrins (other adhesion molecules), a process thought to be implicated in the pathophysiology of Multiple … It is considered a small-molecule prodrug. CDP323 was originally developed by the British biopharmaceutical company Celltech plc.

  6. Drug

    Calendula officinalis flower

    go.drugbank.com/drugs/DB14263
    Approved

    Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  7. Drug

    Rumex crispus whole

    go.drugbank.com/drugs/DB14267
    Approved

    Rumex crispus whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  8. Drug

    Ocimum tenuiflorum top

    go.drugbank.com/drugs/DB14273
    ApprovedWithdrawn

    Ocimum tenuiflorum top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  9. Drug

    Angelica archangelica root

    go.drugbank.com/drugs/DB14283
    Approved

    Angelica archangelica root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  10. Drug

    Kaempferia galanga root

    go.drugbank.com/drugs/DB14288
    ApprovedWithdrawn

    Kaempferia galanga root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.