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Lumefantrine co-artemether
go.drugbank.com/drugs/DB13085ApprovedInvestigationalWithdrawnThe combination is an effective and well-tolerated malaria treatment, providing high cure rates even in areas of multi-drug resistance. … The exact mechanism of action of lumefantrine is not well defined, but it is thought to inhibit -hematin formation, an important detoxification pathway for the parasite.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCefdinir
go.drugbank.com/drugs/DB00535ApprovedInvestigationalCefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially marketed by Abbvie. … Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class.
Synonyms: (6R,7R,Z)-7-(2-(2-aminothiazol-4-yl)-2-(hydroxyimino)acetamido)-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-hydroxyimino]-acetylamino}-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acidInternational brands: Omnicef RPyrophosphoric acid
go.drugbank.com/drugs/DB04160ApprovedInvestigationalMixtures: Dr. DADDYS Tooth, Dr. DADDYS Kids ToothAS1409
go.drugbank.com/drugs/DB05182InvestigationalAS1409 is a genetically engineered fusion protein made up of two distinct components. One is the cytokine IL12, which has anti-cancer activity. The other is an antibody that targets tumours. … It is developed by Antisoma is in a phase I of clinical trial for the treatment of renal cancer and melanoma.
Meningococcal polysaccharide vaccine group A
go.drugbank.com/drugs/DB13889ApprovedInvestigationalIt is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup A. … *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia.
Synonyms: Neisseria meningitidis group A polysaccharide antigen, A, Meningococcal group A polysaccharideMixtures: Menomune - A/c/y/w-135 Combined, Menomune-A/c/y/w-135Meningococcal polysaccharide vaccine group C
go.drugbank.com/drugs/DB13890ApprovedInvestigationalIt is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup C. … *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia.
Synonyms: Meningococcal group C polysaccharide, Meningococcal polysaccharide antigen group CMixtures: Menomune - A/c/y/w-135 Combined, Menomune-A/c/y/w-135Remifentanil
go.drugbank.com/drugs/DB00899ApprovedInvestigationalRemifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. … Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Categories: Heterocyclic Compounds, 1-RingProducts: Remifentanil Kabi 1 mg Pulver zur Herstellung eines Konzentrats für eine Injektions- oder Infusionslösung, Remifentanil Kabi 2 mg Pulver zur Herstellung eines Konzentrats für eine Injektions- oder InfusionslösungDiphenylpyraline
go.drugbank.com/drugs/DB01146ApprovedDiphenylpyraline is an antihistamine. Antihistamines used in the treatment of allergy act by competing with histamine for H 1-receptor sites on effector cells.
Synonyms: 1-methyl-4-piperidyl benzhydryl ether, 4-(benzhydryloxy)-1-methylpiperidineMixtures: Emercidin D Tab, Oradrine 2 TabHuperzine A
go.drugbank.com/drugs/DB04864ApprovedInvestigationalWithdrawnHuperzine A, is a naturally occurring sesquiterpene alkaloid found in the extracts of the firmoss _Huperzia serrata_. … It is currently being investigated as a possible treatment for diseases characterized by neurodegeneration – particularly Alzheimer’s disease.
Synonyms: L-huperzine A, Huperzine ACategories: Compounds used in a research, industrial, or household setting