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Finerenone
go.drugbank.com/drugs/DB16165ApprovedInvestigational[A236544] So far, finerenone is the only nonsteroidal mineralocorticoid receptor antagonist to be FDA approved. … [A236544,L34739] Finerenone was granted FDA approval on 9 July 2021,[L34739] followed by the EMA approval on 11 March 2022.[L41449]
Entrectinib
go.drugbank.com/drugs/DB11986ApprovedInvestigational[L8081] It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors.
Ketamine
go.drugbank.com/drugs/DB01221ApprovedInvestigationalVet approvedIt was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients undergoing minor surgeries but mainly for veterinary purposes.[L1332]
Cilgavimab
go.drugbank.com/drugs/DB16393ApprovedInvestigational[A243351, A243361, L39411] Cilgavimab is not approved for any indication by the FDA. … The FDA and Health Canada advise healthcare providers to inform patients of this risk.[L43772,L43777]
Tixagevimab
go.drugbank.com/drugs/DB16394ApprovedInvestigational[A243351, A243361, L39411] Tixagevimab is not approved for any indication by the FDA. … The FDA and Health Canada advise healthcare providers to inform patients of this risk.[L43772,L43777]
Magnesium Aluminum Silicate
go.drugbank.com/drugs/DB11230ApprovedWithdrawnMagnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group . It is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking agent, opac...
Imdevimab
go.drugbank.com/drugs/DB15940ApprovedInvestigationalCasirivimab and imdevimab are investigational recombinant human IgG1 monoclonal antibodies that, at this time, are not officially approved by the FDA. … [A221495] On November 21, 2020, the FDA authorized emergency approval of REGN-COV2 to treat mild to moderate COVID-19 in patients aged 12 years and older.
Silanol
go.drugbank.com/drugs/DB11343ApprovedSilanol is an FDA-approved food contact substance that is commonly used in organosilicon chemistry and silicate mineralogy.
Sulfasalazine
go.drugbank.com/drugs/DB00795ApprovedInvestigationalIt is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA). … [A255582] Although sulfasalazine is only approved by the FDA for ulcerative colitis, research have shown that sulfasalazine is also beneficial for patients with Crohn's disease.
Products: PLEON RA, AZULFIDINE RAEpinephrine
go.drugbank.com/drugs/DB00668ApprovedInvestigationalVet approvedEpinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersen...