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Displaying results 411 - 420 of 10000 in total
  1. Drug

    Baclofen

    go.drugbank.com/drugs/DB00181
    ApprovedInvestigational

    [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977. … Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients.

    Categories: Amino Acids, Peptides, and ProteinsProducts: LIORESAL 25MG, LIORESAL 10MG
  2. Drug

    Valerian

    go.drugbank.com/drugs/DB13196
    Approved

    Valerian has been used in the treatment of conditions including sleep disorders, anxiety, attention deficit-hyperactivity disorder (ADHD) and joint pain. … Valerian is extracted from a herb that is a perennial flowering plant. Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is not completely understood.

    Mixtures: Herbal Slumber Cap, Valerian and Hops TabletsCategories: Hypnotics and Sedatives, Herbs and Natural Products
  3. Drug

    Maprotiline

    go.drugbank.com/drugs/DB00934
    Approved

    It differs from TCAs in that it does not appear to block serotonin reuptake. … Maprotiline may be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and major depressive disorder.

    Categories: Tricyclics and Other Norepinephrine-reuptake InhibitorsProducts: Ludiomil Tab 10mg, Novo-maprotiline - Tab 10mg
  4. Drug

    Dantrolene

    go.drugbank.com/drugs/DB01219
    ApprovedInvestigational

    Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.

    Categories: Dantrolene and DerivativesProducts: Dantrium Cap 25mg, Dantrium Cap 100mg
  5. Drug

    Fexofenadine

    go.drugbank.com/drugs/DB00950
    ApprovedInvestigational

    Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. … [L4269] It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation

    Mixtures: Foster and Thrive Allergy and Congestion D, Allergy and CongestionProducts: Up and Up Allergy Relief, Up and Up Non Drowsy Allergy Relief
  6. Drug

    Testosterone

    go.drugbank.com/drugs/DB00624
    ApprovedInvestigational

    [A187114,L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone was isolated from samples and also synthesized in 1935.[A186943] … Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.

    Categories: Androgens and Estrogens, testosterone and estrogenInternational brands: Testaqua IM
  7. Drug

    Izuralimab

    go.drugbank.com/drugs/DB18933
    Investigational

    Izuralimab is under investigation in clinical trial NCT05879185 (A Study of Xmab23104 in People With Sarcoma).

    Synonyms: IMMUNOGLOBULIN HALF-IG G1-KAPPA/SCFV-H-CH2-CH3, ANTI-(HOMO SAPIENS ICOS (INDUCIBLE T-CELL COSTIMULATORY, ACTIVATION-INDUCIBLE LYMPHOCYTE IMMUNOMEDIATORY MOLECULE, AILIM, CD278)) AND ANTI-(HOMO SAPIENS
  8. Drug

    Vitamin A

    go.drugbank.com/drugs/DB00162
    ApprovedInvestigationalNutraceuticalVet approved

    Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the … Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.

    Mixtures: Vitamin A and D Cap, Vitamin A and D CapCategories: Alimentary Tract and Metabolism, Diet, Food, and Nutrition
  9. Drug

    Clotrimazole

    go.drugbank.com/drugs/DB00257
    ApprovedInvestigationalVet approved

    It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). … As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094].

    Mixtures: METRONIDAZOL / CLOTRIMAZOL 500MG / 100MG OVULO VAGINAL, MYKOFUNGIN 3 200MG+10MG/GCategories: Imidazole and Triazole Derivatives, Gynecological Antiinfectives and Antiseptics
  10. Drug

    Larotrectinib

    go.drugbank.com/drugs/DB14723
    ApprovedInvestigational

    an important role in tumor cell growth and survival. … Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays

    Categories: Antineoplastic and Immunomodulating AgentsProducts: VITRAKVI ORAL SOLUTION 20MG/ML, VITRAKVI HARD CAPSULE 25MG