Valerian

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Valerian
Accession Number
DB13196
Description

Valerian is extracted from a herb that is a perennial flowering plant. Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is not completely understood. Valerian has been used in the treatment of conditions including sleep disorders, anxiety, attention deficit-hyperactivity disorder (ADHD) and joint pain. Valproic acid is a derivative of valeric acid, which is obtained from the plant root. Valerian is a food ingredient permitted for direct addition to food for human consumption as a natural flavoring substance.

Type
Biotech
Groups
Approved, Experimental, Investigational
Biologic Classification
Allergenics
Allergen Extract
Synonyms
  • Valerianae radix

Pharmacology

Pharmacology
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Indication
Not Available
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
Medicalerrors
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Products
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Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Artryl Cap 200 mgCapsuleOralLes Laboratoires Vachon Inc.1994-12-312007-07-12Canada flag
Effidose Valeriane Liq 1916mg/10ml AmpLiquidOralLaboratoires Charton Laboratories1995-12-311999-01-16Canada flag
Ethical Herbals Sleep AidTabletOralAshbury Research CorporationNot applicableNot applicableCanada flag
Facilite Le Sommeil - Cap 270mgCapsuleOralLaboratoire Lalco Inc.1997-01-202002-09-05Canada flag
Hermes No6 TeaLiquidOralHermes Arzneimittel Gmbh1958-12-311999-07-08Canada flag
Kalm CapsCapsuleOralRheingold Food International Ltd.1985-12-312001-07-06Canada flag
Nervatex Tab 500mgTabletOralCarmaran LtÉe1980-12-311996-09-09Canada flag
Nervatex Tablets 500mgTabletOralPharmetics (2011) Inc.1995-12-312000-08-21Canada flag
PhytocalmCapsuleOralSantÉ Naturelle (Ag) LtÉe1998-12-132004-08-05Canada flag
Salus Valerian TctTinctureOralSalus Haus1979-12-312003-07-24Canada flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Bio-strath No. 8 GouttesValerian (0.225 ml) + Passiflora incarnata flower (0.225 ml) + Peppermint (0.05 ml)Solution / dropsOralBio Strath Ag1989-12-312008-07-24Canada flag
Dormiphen Au NaturelValerian (400 mg) + Passiflora incarnata flower (400 mg)CapsuleOralLaboratoire Lalco Inc.Not applicableNot applicableCanada flag
Herbal Nerve - TabletValerian (300 mg) + Scutellaria lateriflora (350 mg)TabletOralSwiss Herbal Remedies Ltd.1995-12-312009-08-04Canada flag
Herbal Nerve TabValerian (50 mg) + Hops (50 mg) + Scutellaria lateriflora (100 mg)TabletOralVita Health Products Inc1977-12-312005-07-20Canada flag
Herbal RelaxValerian (120 mg) + Chamomile (460 mg)CapsuleOralWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.1998-11-052002-07-29Canada flag
Herbal Relaxant - TabletValerian (500 mg) + Chamomile (200 mg)TabletOralQuest Vitamins A Div Of Purity Life Health Products1995-12-312001-07-06Canada flag
Herbal SleepValerian (600 mg) + Chamomile (100 mg) + Hops (165 mg) + Passiflora incarnata flower (175 mg)CapsuleOralPuresource Inc.Not applicableNot applicableCanada flag
Herbal Sleep AidValerian (400 mg) + Hops (100 mg) + Passiflora incarnata flower (100 mg)CapsuleOralWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.1998-11-052002-07-29Canada flag
Herbal Slumber CapValerian (177 mg) + Hops (67 mg) + Peppermint (153 mg) + Scutellaria lateriflora (153 mg)CapsuleOralPep Products Inc.1992-12-311999-10-29Canada flag
Hops-valerian Combination CapValerian (133 mg) + Hops (134 mg) + Scutellaria lateriflora (133 mg)CapsuleOralNature's Herbs Inc.1995-12-311997-05-30Canada flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Medi-doze Rx Sleep AidValerian (50 mg/1) + Melatonin (6 mg/1) + gamma-Aminobutyric acid (30 mg/1)TabletOralTwo Hip Consulting, Llc2013-02-202016-04-11US flag

Categories

ATC Codes
N05CM09 — Valerianae radix
Drug Categories
Classification
Not classified

Chemical Identifiers

UNII
JWF5YAW3QW
CAS number
8057-49-6

References

General References
Not Available
PubChem Substance
347911444
RxNav
253206
Wikipedia
Valerian
AHFS Codes
  • 92:01.00* — Herbs and Natural Products
  • 28:24.92 — Miscellaneous Anxiolytics Sedatives and Hypnotics

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3CompletedTreatmentAnxiety Disorders1
3Unknown StatusTreatmentAnxiety Disorders1
Not AvailableCompletedPreventionBlood Pressures / Dental Anxiety / Heart Rate1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
CapsuleOral270 MG
Solution / dropsOral
LiquidOral
Injection, solutionIntramuscular100 mg/2ml
SyrupOral10 mg/ml
TabletOral40 MG
TabletOral
CapsuleOral
PowderOral
For solutionOral400 MG
TinctureOral
Tablet, coated100 MG
Tablet, coated125 MG
Tablet, coated135 MG
Tablet, coated45 MG
Tablet, coatedOral200 mg
Tablet, coated50 MG
Tablet, coated450 MG
TabletOral
CapsuleOral
LiquidOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on June 23, 2017 20:37 / Updated on February 24, 2021 19:34