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Imexon
go.drugbank.com/drugs/DB05003InvestigationalImexon is currently being studied for the treatment of pancreatic, lung, breast, prostate, melanoma, and multiple myeloma cancers. It belongs to the family of drugs called cyanoaziridine derivatives. … Imexon is a cyanoaziridine derivative. Imexon is a thiol-binding small molecule which induces mitochondrial oxidation, a loss of membrane potential and cytochrome C, leading to apoptosis.
Sirna-027
go.drugbank.com/drugs/DB05896InvestigationalIt is used to treat Macular degeneration. … VEGFR-1 is a key component of the clinically validated vascular endothelial growth factor (VEGF) pathway. Sirna-027 is developed by Sirna Therapeutics and is under the phase I of clinical trails.
4-dimethylaminophenol
go.drugbank.com/drugs/DB13549ExperimentalCategories: Compounds used in a research, industrial, or household settingGleptoferron
go.drugbank.com/drugs/DB11417ExperimentalVet approvedColloid solution of ferric hydroxide, dextran & glucoheptonic acid.
Categories: Compounds used in a research, industrial, or household settingBimakalim
go.drugbank.com/drugs/DB19948ExperimentalBimakalim is a small molecule drug. The usage of the INN stem '-kalim' in the name indicates that Bimakalim is a potassium channel activator, antihypertensive.
Categories: Compounds used in a research, industrial, or household settingNisin Z
go.drugbank.com/drugs/DB19122InvestigationalNisin Z is under investigation in clinical trial NCT06097468 (Nisin in Oral Cavity Squamous Cell Carcinoma (OCSCC)).
Categories: Compounds used in a research, industrial, or household settingAmetantrone
go.drugbank.com/drugs/DB21078ExperimentalAmetantrone is a small molecule drug. Ametantrone has a monoisotopic molecular weight of 412.21 Da.
Categories: Compounds used in a research, industrial, or household settingLevmetamfetamine
go.drugbank.com/drugs/DB09571ApprovedLevomethamphetamine, the L-enantiomer of methamphetamine is a sympathomimetic vasoconstrictor used in some over-the-counter (OTC) nasal decongestant inhalers in the United States.
Sofalcone
go.drugbank.com/drugs/DB05197ExperimentalSofalcone is a mucosal protective agent that has been reported to inhibit growth of Helicobacter pylori. on adherence, production of vacuolating toxin (VT), and induction of interleukin-8 (IL-8) secretion
Diacerein
go.drugbank.com/drugs/DB11994ApprovedInvestigationalWithdrawnIt is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including severe diarrhea [L780]. … Diacerein is a prodrug which is metabolized to rhein.