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Viper antivenom
go.drugbank.com/drugs/DB14114ApprovedInvestigationalANAVIP, an equine-derived antivenom made with venom from _Bothrops asper_ and _Crotalus durissus_, was first approved by the FDA on October 1, 2015, for the management of North American rattlesnake envenomation
Synonyms: Crotalidae immune F(ab')2 (equine), Antivenin crotaline (pit-viper) equine immune F(ab)2)Tiagabine
go.drugbank.com/drugs/DB00906ApprovedTiagabine is an anti-convulsive medication. It is also used in the treatment for panic disorder as are a few other anticonvulsants. … Though the exact mechanism by which tiagabine exerts its effect on the human body is unknown, it does appear to operate as a selective GABA reuptake inhibitor.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAmrinone
go.drugbank.com/drugs/DB01427ApprovedWithdrawnAmrinone (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.
Categories: Heterocyclic Compounds, 1-Ring, Phosphodiesterase 3 InhibitorsZidebactam
go.drugbank.com/drugs/DB13090ApprovedZidebactam is a diazabicyclooctane that acts both as a beta-lactamase inhibitor and as an antibacterial in its own right, selectively binding penicillin-binding protein 2. … [L63932] Wockhardt announced FDA approval of the cefepime-zidebactam combination on May 30, 2026, for adults with complicated urinary tract infections, including pyelonephritis, caused by designated
Categories: Heterocyclic Compounds, 1-RingOspemifene
go.drugbank.com/drugs/DB04938ApprovedOspemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause
Synonyms: 2-(p-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanol, 2-(4-(4-Chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesDG051
go.drugbank.com/drugs/DB05177ExperimentalDG051 is designed to decrease risk of heart attack by decreasing the production of leukotriene B4 (LTB4), an end product of the leukotriene pathway and a potent promoter of inflammation. … DG051 is a novel small-molecule inhibitor of leukotriene A4 hydrolase (LTA4H), the protein made by one of the genes in the leukotriene pathway that has been shown to link to risk of heart attack.
Cerulenin
go.drugbank.com/drugs/DB01034ExperimentalCerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. … In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity.
Synonyms: (2R,3S)-3-((4E,7E)-nona-4,7-dienoyl)oxirane-2-carboxamide, (2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amideDe Novo Triacylglycerol Biosynthesis TG(16:0/16:1(9Z)/20:0)
smpdb.ca/view/SMP0015920MetabolicTriglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. … (Wikipedia) De novo biosynthesis of triglycerides is also known as the phosphatidic acid pathway, and it is mainly associated with the liver and adipose tissue.
De Novo Triacylglycerol Biosynthesis TG(18:0/18:0/18:1(9Z))
smpdb.ca/view/SMP0015940MetabolicTriglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. … (Wikipedia) De novo biosynthesis of triglycerides is also known as the phosphatidic acid pathway, and it is mainly associated with the liver and adipose tissue.
De Novo Triacylglycerol Biosynthesis TG(18:0/20:0/20:1(11Z))
smpdb.ca/view/SMP0015945MetabolicTriglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. … (Wikipedia) De novo biosynthesis of triglycerides is also known as the phosphatidic acid pathway, and it is mainly associated with the liver and adipose tissue.