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Displaying results 4191 - 4200 of 10000 in total
  1. Drug

    Carmustine

    go.drugbank.com/drugs/DB00262
    ApprovedInvestigational

    A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985).

    Synonyms: N,N'-Bis(2-chloroethyl)-N-nitrosoureaCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  2. Drug

    Pentamidine

    go.drugbank.com/drugs/DB00738
    ApprovedInvestigational

    Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other t...

    Synonyms: 1,5-bis(4-amidinophenoxy)pentane, p,p'-(pentamethylenedioxy)dibenzamidineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  3. Drug

    N-[(E)-3-[(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]prop-2-enyl]-2,3-dihydroxy-5-nitrobenzamide

    go.drugbank.com/drugs/DB03907
    Experimental

    Synonyms: N-[(E)-3-[(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]prop-2-enyl]-2,3-dihydroxy-5-nitrobenzamide
  4. Drug

    Tigulixostat

    go.drugbank.com/drugs/DB18799
    Investigational

    Synonyms: 1h-pyrazole-4-carboxylic acid, 1-(3-cyano-1-(1-methylethyl)-1h-indol-5-yl)-
  5. Drug

    (S)-AMPA

    go.drugbank.com/drugs/DB02057
    Experimental

    AMPA is a specific agonist for the AMPA receptor.

    Synonyms: (S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, L-AMPA
  6. Drug

    CP-271485

    go.drugbank.com/drugs/DB02118
    Experimental

    Synonyms: (6S)-4-Benzyl-6-(1-methyl-2,2-dioxido-1,3-dihydro-2,1-benzothiazol-5-yl)-3-morpholinone
  7. Drug

    1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE

    go.drugbank.com/drugs/DB04685
    Experimental

    Synonyms: 1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE
  8. Drug

    N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE

    go.drugbank.com/drugs/DB07562
    Experimental

    Synonyms: N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE
  9. Drug

    Almitrine

    go.drugbank.com/drugs/DB01430
    Approved

    Almitrine is a respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. … It is also reported to have a potentially beneficial effect in treating the noctural oxygen desaturation without impairing the quality of sleep.

    Synonyms: 2,4-Bis(allylamino)-6-(4-(bis(p-fluorophenyl)methyl)-1-piperazinyl)-s-triazineCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-Ring
  10. Drug

    Zanidatamab

    go.drugbank.com/drugs/DB15471
    ApprovedInvestigational

    Zanidatamab is a bispecific antibody that binds two non-overlapping sites of HER2 (ERBB2).

    Synonyms: IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS ERBB2 (EPIDERMAL GROWTH FACTOR RECEPTOR 2, RECEPTOR TYROSINEPROTEIN KINASE ERBB-2, EGFR2, HER2, HER-2, P185C-ERBB2, NEU, CD340)), HUMANIZED MONOCLONAL ANTIBODYCategories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors